Results 111 to 120 of about 3,038,437 (295)

Stress Transfer From Slow Slip Events to Earthquake Swarms as a Cycle in the Southernmost Ryukyu Subduction Zone

open access: yesGeophysical Research Letters
Recent megathrust earthquakes preceded by slow slip events highlight static stress transfer as a key triggering mechanism. However, there are limited insights into the interplay between static stress transfer and elevated fluid pressure before earthquake
Sean Kuanhsiang Chen   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Interaction of multiple triggering mechanisms during the 2023 Jishishan earthquake sequence

open access: yesCommunications Earth & Environment
Post-seismic processes of moderate earthquakes are often overlooked due to their limited rupture extent and uncertainties in source parameters and aftershock catalogs, leading many studies to assume a single triggering mechanism.
Zhe Zhang   +6 more
doaj   +1 more source

Putting faults in the northern Chilean subduction margin into motion: evidence for remote dynamic earthquake triggering on the plate interface and within the forearc

open access: yesSeismica
Dynamic stresses on the order of ~1 kPa from passing waves of mainshock earthquakes can trigger aftershocks at remote distances. Here, we investigate the prevalence of remote earthquake triggering in northern Chile, where aseismic-slip triggering has ...
Rebecca Harrington   +4 more
doaj   +1 more source

Mimetics of Hormetic Agents: Stress-Resistance Triggers

open access: yesDose-Response, 2010
Mimetics of hormetic agents offer a novel approach to adjust dose to minimize the risk of toxic response, and maximize the benefit of induction of at least partial physiological conditioning. Nature selected and preserved those organisms and triggers that promote tolerance to stress.
openaire   +3 more sources

A unified model for dynamic and static stress triggering of aftershocks, antishocks, remote seismicity, creep events, and multisegmented rupture.

open access: yes, 2004
International audienceAftershocks have been thought to be triggered by static stress transfer. The 1992 Landers and 1999 Hector Mine, California, earthquakes have demonstrated the possibility of remote triggering of seismicity, highlighting the role of ...
Di Carli, S.   +6 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Long-period microseismicity reveals cryptic earthquake-triggered fluid activity can facilitate caldera eruptions

open access: yesNature Communications
Spatiotemporal correlations between moderate-to-large earthquakes and volcanic eruptions indicate that earthquake-induced stress changes can trigger eruptions.
Zilin Song   +7 more
doaj   +1 more source

Evolution and triggering mechanism of fault-slip rockbursts in deep tunnels: Insights from 3D printed large-scale physical models

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
The excavation of deep tunnels crossing faults is highly prone to triggering rockburst disasters, which has become a significant engineering issue.
Shi-Ming Mei   +5 more
doaj   +1 more source

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