Results 71 to 80 of about 3,038,437 (295)

Stress triggering and the Canterbury earthquake sequence

, 2014
The Canterbury earthquake sequence, which includes the devastating Christchurch event of 2011 February, has to date led to losses of around 40 billion NZ dollars.
Steacy, S., Holden, C., Jimenez, A.
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Low-Triggering-Potential Electrochemiluminescence from Surface-Confined CuInS2@ZnS Nanocrystals and their Biosensing Applications

, 2021
Electrochemiluminescence (ECL) of low triggering potential is strongly anticipated for ECL assays with less inherent electrochemical interference and improved long-term stability of the working electrode.
Jingna Jia (7429583), Guizheng Zou, Xuwen Gao, Jingna Jia, Li Fu (85791), Shuangtian Dong (9962350), Guizheng Zou (1412527), Shuangtian Dong, Xuwen Gao (375540), Li Fu   +9 more
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Coseismic Coulomb stress changes induced by a 2020–2021 MW > 7.0 Alaska earthquake sequence in and around the Shumagin gap and its influence on the Alaska-Aleutian subduction interface

Geodesy and Geodynamics
Three MW > 7.0 earthquakes in 2020–2021 occurred in the Shumagin seismic gap and its adjacent area of the Alaska-Aleutian subduction zone, including the MW7.8 Simeonof thrust earthquake on July 22, 2020, the MW7.6 Sand Point strike-slip earthquake on ...
Lei Yang, Jianjun Wang, Caijun Xu
doaj   +1 more source

Nightmare as a trigger for stress cardiomyopathy

Cardiology Journal, 2023
Arcens, Marc, Noble, Stéphane Laurent
openaire   +2 more sources

Stress-Triggered Changes in Peripheral Catecholaminergic Systems [PDF]

, 2013
The sympathetic nervous system not only regulates cardiovascular and metabolic responses to stress but also is altered by stress. The sympathoneural and sympathoadrenomedullary systems are modified by different metabolic pathways and have different responses to short- and to long-term stressors.
Kvetnansky, Richard, Lu, Xiaojiong, Ziegler, Michael G   +2 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source