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Stress Ulcer Prophylaxis for Critical Asthma
Pediatrics, 2022BACKGROUND Children hospitalized for critical asthma (CA) in the pediatric ICU (PICU) are commonly prescribed stress ulcer prophylaxis (SUP) to mitigate risk of gastrointestinal (GI) bleeding. We sought to describe trends for SUP prescribing and explore for differences in rates of GI bleeding, gastritis, and SUP ...
Alexa Rae, Roberts +5 more
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The Prophylaxis of Stress Ulceration
New England Journal of Medicine, 1980What is and what is not stress ulceration? The development of multiple erosions in the gastric or duodenal mucosa of acutely ill patients characterizes this condition.
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Critical Care Medicine, 2004
Preview Which critically ill patients are at increased risk for gastrointestinal hemorrhage from stress ulcers? Do prophylactic agents effectively reduce the morbidity and mortality associated with stress-related hemorrhage? The author, former director of a medical intensive care unit, reviews recent literature on stress ulcer prophylaxis and outlines ...
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Preview Which critically ill patients are at increased risk for gastrointestinal hemorrhage from stress ulcers? Do prophylactic agents effectively reduce the morbidity and mortality associated with stress-related hemorrhage? The author, former director of a medical intensive care unit, reviews recent literature on stress ulcer prophylaxis and outlines ...
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Stress Ulcer Prophylaxis in Neurocritical Care
Neurocritical Care, 2017Stress ulcer prophylaxis (SUP) with acid-suppressive drug therapy is widely utilized in critically ill patients following neurologic injury for the prevention of clinically important stress-related gastrointestinal bleeding (CIB). Data supporting SUP, however, largely originates from studies conducted during an era where practices were vastly different
Jeffrey F, Barletta +3 more
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National survey of stress ulcer prophylaxis
Critical Care Medicine, 1999To determine the rationale for using stress ulcer prophylaxis (SUP) among clinicians; to assess criteria used to define failure of SUP; and to evaluate the decision-making process in the selection of a prophylactic agent.A cross-sectional national mail survey.Random sample of the members of the Society of Critical Care Medicine who identified ...
N P, Lam +3 more
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Stress ulcer prophylaxis in the postoperative period
American Journal of Health-System Pharmacy, 2004The implications of recent studies for guidelines that pertain to stress ulcer prophylaxis in the postoperative period are discussed.The therapeutic guidelines on stress ulcer prophylaxis published by the American Society of Health-System Pharmacists (ASHP) provided clinicians with recommendations regarding appropriate candidates for stress ulcer ...
Michelle E, Allen +2 more
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PURPOSE: Most intensive care unit (ICU) patients receive stress ulcer prophylaxis. We present updated evidence on the effects of prophylactic proton pump inhibitors (PPIs) or histamine 2 receptor antagonists (H2RAs) versus placebo/no prophylaxis on ...
Marija Barbateskovic +2 more
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Current Guidelines on Stress Ulcer Prophylaxis
Drugs, 1997Acute uppergastrointestinal bleeding in intensive care unit (ICU) patients may occur due to peptic ulcer disease, adverse drug effects, gastric tube lesions, acute renal failure, liver failure or stress-induced gastric mucosal lesions. Gastric acid hypersecretion can be observed in patients with head trauma or neurosurgical procedures.
M, Tryba, D, Cook
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Methods of prophylaxis in stress ulcer disease
World Journal of Surgery, 1981AbstractAlthough infrequent, acute upper gastrointestinal bleeding is potentially life‐threatening for critically ill patients. Gastric erosions can be detected endoscopically in almost all seriously ill patients. Although gastric acid plays a key role in the pathogenesis of acute gastric erosions, mucosal integrity is very much dependent on mucosal ...
Priebe, Hans-Joachim, Skillman, John J.
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Stress Ulcer Prophylaxis in the ICU
Critical Care Medicine, 2013Bleeding from stress-related mucosal disease (SRMD) in critically ill patients remains an important clinical management issue. Although only a small proportion (2% to 6%) of patients admitted to an ICU setting will bleed (1), a significant proportion exhibit the clinical risk factors, mainly mechanical ventilation for more than 48 hrs and the presence ...
Marc, Bardou, Alan N, Barkun
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