Results 211 to 220 of about 5,748,260 (338)

Biomechanical Effects of Platform Diameter and Screw Length in an Abutment-Free Tissue-Level Implant System Compared with a Ti-Base Configuration: 3D Finite Element Analysis. [PDF]

J Funct Biomater
Dodi A, Ionescu A, Marin MA, Nuțu E, Vasilescu VG, Țâncu AMC, Ciocan TL, Imre M.   +7 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Resistance of cervical vertebrae in response to muscular stresses in pterosaurs: implications for foraging habits and skeletal pneumatization. [PDF]

PeerJ
Buchmann R, Rodrigues T.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Forward and inverse optimality problems of bone adaptation at the homogenised RVE level. [PDF]

Biomech Model Mechanobiol
Zysset PK.
europepmc   +1 more source

Methods and concepts in quantifying resistance to drought, salt and freezing, abiotic stresses that affect plant water status.

The Plant Journal, 2006
P. Verslues, Manu Agarwal, Surekha Katiyar-Agarwal, Jianhua Zhu, Jianhua Zhu   +4 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Extreme heat and drought at flowering could threaten global wheat yields under climate change. [PDF]

Clim Change
Senapati N, Halford NG, Hawkesford MJ, Shewry PR, Semenov MA.   +4 more
europepmc   +1 more source

Residual stresses in selective laser sintering and selective laser melting

, 2006
P. Mercelis, J. Kruth
semanticscholar   +1 more source

Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

Journal of Experimental Biology, 2005
P. Yancey
semanticscholar   +1 more source