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Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Aneuploidy confers environmentally robust higher evolvability than euploidy in a synthetic allotetraploid wheat. [PDF]

Sci Adv
Wang H, Wang R, Chen B, Aslam T, Lian T, Xu C, Liu B, Lv R.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Influence Mechanism of N₂-CO₂ Mixtures on the CH₄ Displacement Behavior from Different Coal Samples under Stress Condition. [PDF]

ACS Omega
Li Y, Lv R, Qiao L, Yang X, Wu H, Wang X.   +5 more
europepmc   +1 more source

Analysis of twist-rate effects in a progressive-rifling barrel using finite element method. [PDF]

Sci Prog
Lai CC, Deng S, Lin CC.
europepmc   +1 more source

The number of fusion levels as a potential factor influencing long-term complications of anterior controllable antedisplacement fusion: a biomechanical analysis. [PDF]

Front Surg
He G, Li H, Yan L, Liu Z, Lu T.
europepmc   +1 more source

Conserved mechanisms of plant lipidome remodeling under heat and cold stresses revealed through a systematic review and meta-analysis. [PDF]

J Exp Bot
Sathasivam M, Allen DK, Shankar V, Saha R, Narayanan S.   +4 more
europepmc   +1 more source

Integrative cross-study analysis of maize microarray datasets identifies key abiotic stress-responsive genes, highlighting ZmOSM34 and ZmANAH. [PDF]

Sci Rep
Zamani E, Razi H, Hildebrand D, Alemzadeh A.   +3 more
europepmc   +1 more source

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Silicon (Si): Review and future prospects on the action mechanisms in alleviating biotic and abiotic stresses in plants

Ecotoxicology and Environmental Safety, 2018
Byoung Ryong Jeong, Hassan Etesami
exaly   +2 more sources

Abiotic stress-induced anthocyanins in plants: Their role in tolerance to abiotic stresses.

Physiologia Plantarum : An International Journal for Plant Biology, 2021
Abiotic stress, such as heat, drought, salinity, low temperature, and heavy metals, inhibit plant growth and reduce crop productivity. Abiotic stresses are becoming increasingly extreme worldwide due to the ongoing deterioration of the global climate and
A. H. Naing, C. Kim
semanticscholar   +1 more source