Results 241 to 250 of about 1,921,038 (288)

Engineering Stability: Cholesterol-Modulated Liposome Response to Physical and Chemical Stressors for Enhanced Antimicrobial Activity. [PDF]

Pharmaceuticals (Basel)
Ribeiro LM, Bonatto CC, Silva LP.
europepmc   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Morphodynamics of surface-attached active drops. [PDF]

Nat Commun
Martínez-Calvo A, Datta SS.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Nanoscale Undulation of Elastic Fields During Deformation Twinning in FCC Metals. [PDF]

Materials (Basel)
Qiu D, Zhao P.
europepmc   +1 more source

Understanding the mechanisms of TAVI durability through computational modelling: a multidisciplinary review. [PDF]

Eur Heart J Digit Health
Rauseo E, Bevis L, Chen X, Petersen SE, Mathur A, Slabaugh GG, Roney CH.   +6 more
europepmc   +1 more source

Numerical validation of the applicability of the simplified ventricular model in the analysis of hemolysis in the mitral paravalvular leak. [PDF]

Front Bioeng Biotechnol
Truchel K, Wojtas K, Marchel M, Orciuch W, Makowski Ł.   +4 more
europepmc   +1 more source

Challenges and Best Practices in Modeling Anisotropic Stresses in Soft Polymorphic Materials. [PDF]

ACS Phys Chem Au
Neirynck J, Geerinckx S, Rogge SMJ.
europepmc   +1 more source