Results 61 to 70 of about 747,930 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Challenges of measuring residual stresses in large girth welded pipe spools by neutron diffraction [PDF]
, 2016 In this paper, welding induced residual stresses in a welded API 5L X65 girth pipe spools are discussed in as-welded and in local post weld heat treated conditions.
Eren, E, Wang, B, Yao, R, Paradowska, A
core +1 more source
, 2022 S.262-268The incremental hole-drilling method was adapted for the measurement of residual stresses in polymer based composite materials. The parameters of the hole drilling process and the strain measurement in non-reinforced and 70 weight-percent glass ...
Schweizer, F., Luke, M., Dickele, M.
core +1 more source
Biophysical Journal, 2013 Cultivated animal cells often display prominent actin bundles, also known as stress fibers, throughout their cytoskeleton. These bundles are thought to provide mechanical tension and might take part in cellular mechanosensing. To test the functions of these bundles we cultivated endothelial cells on soft silicone elastomer films.
Zielinski, Alexander +4 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Stresses in Saturated and Unsaturated Subgrade Layer Induced by Railway Track Vibration
InfrastructuresThe theoretical and practical studies of the cyclic loads resulting from the movement and passage of trains on the unsaturated subgrade to determine the effect of the degree of saturation and moisture content on the foundations and infrastructure of the ...
Mohammed Y. Fattah +2 more
doaj +1 more source
Additional Pressure Distribution on Subway Tunnels from Ground Construction
Civil and Environmental Engineering, 2022 In the proposed research there were evaluated the factors influencing the distribution of additional pressure from ground construction on the linings of the subway tunnels. In recent years, the Department of Tunnels and Subways of the Emperor Alexander I
Sokornov A. +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Direct comparison between rotational and extrusion rheometers
Materials Research, 2009 The use of cone and plate rotational rheology to characterize the flow properties of concentrated dispersion and extrusion methods to determine the rheological properties of pastes have become established rheometric techniques.
Asad Ullah Khan +2 more
doaj +1 more source