Results 131 to 140 of about 192,251 (301)
Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for normal ...
Yeunkum Lee +5 more
doaj +1 more source
This review explores the common pathological mechanisms underlying Alzheimer's disease (AD) and Parkinson's disease (PD), with an emphasis on glucose metabolism and insulin resistance. We examine how disruptions in glucose metabolism and insulin resistance influence the onset and advancement of both Alzheimer's disease (AD) and Parkinson's disease (PD).
Shun‐yu Yao +5 more
wiley +1 more source
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu +7 more
wiley +1 more source
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim +12 more
wiley +1 more source
Transmucosal marker delivery to striatum over time.
A) Fluorescent microscopic images demonstrating transmucosal rhodamine-dextran delivery to the striatum(bregma 1.18 mm, bar = 0.5 mm, 72 h). Diffusion into the right striatum(ipsilateral to mucosal graft) occurs in a molecular weight dependent fashion ...
Richie E. Kohman (406397) +4 more
core +1 more source
Gephyrin Neurological Autoimmunity
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano +10 more
wiley +1 more source
Trimma striatum (Herre 1945) —Stripedhead dwarfgoby Status at New Ireland. New record, based on USNM 262017 (1) from Nusa Island, Kavieng District. A specimen photographed at Lissenung Island, Kavieng District, at 6 m depth, by Dean Tully on 7 July 2011. NTUM 10565 (1 specimen, St.
Andréfouët, Serge +6 more
openaire +2 more sources
PROCESSING OF SMOKING AND MONETARY REWARDS AMONG CHRONIC SMOKERS: CHARACTERIZATION OF NEURAL RESPONSE, MODERATION BY ABSTINENCE, AND ASSOCIATION WITH SMOKING OUTCOMES [PDF]
Theoretical models suggest that chronic smoking may be associated with both hypersensitivity to smoking and related cues and hyposensitivity to alternative reinforcers, and that these effects may be more pronounced during deprivation from smoking ...
Sweitzer, Maggie
core

