Results 131 to 140 of about 192,251 (301)

Transcriptome analyses suggest minimal effects of Shank3 dosage on directional gene expression changes in the mouse striatum

open access: yesAnimal Cells and Systems, 2019
Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for normal ...
Yeunkum Lee   +5 more
doaj   +1 more source

Corpus striatum

open access: yes, 1997
Corpus striatum. Coronal plane.

core  

Shared Metabolic–Proteinopathy Axis in Alzheimer's Disease and Parkinson's Disease: Evidence for a Convergent but Not Identical Disease Spectrum

open access: yesAGING MEDICINE, EarlyView.
This review explores the common pathological mechanisms underlying Alzheimer's disease (AD) and Parkinson's disease (PD), with an emphasis on glucose metabolism and insulin resistance. We examine how disruptions in glucose metabolism and insulin resistance influence the onset and advancement of both Alzheimer's disease (AD) and Parkinson's disease (PD).
Shun‐yu Yao   +5 more
wiley   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu   +7 more
wiley   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim   +12 more
wiley   +1 more source

Transmucosal marker delivery to striatum over time.

open access: yes, 2013
A) Fluorescent microscopic images demonstrating transmucosal rhodamine-dextran delivery to the striatum(bregma 1.18 mm, bar = 0.5 mm, 72 h). Diffusion into the right striatum(ipsilateral to mucosal graft) occurs in a molecular weight dependent fashion ...
Richie E. Kohman (406397)   +4 more
core   +1 more source

Gephyrin Neurological Autoimmunity

open access: yesAnnals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano   +10 more
wiley   +1 more source

Trimma striatum

open access: yes, 2019
Trimma striatum (Herre 1945) —Stripedhead dwarfgoby Status at New Ireland. New record, based on USNM 262017 (1) from Nusa Island, Kavieng District. A specimen photographed at Lissenung Island, Kavieng District, at 6 m depth, by Dean Tully on 7 July 2011. NTUM 10565 (1 specimen, St.
Andréfouët, Serge   +6 more
openaire   +2 more sources

PROCESSING OF SMOKING AND MONETARY REWARDS AMONG CHRONIC SMOKERS: CHARACTERIZATION OF NEURAL RESPONSE, MODERATION BY ABSTINENCE, AND ASSOCIATION WITH SMOKING OUTCOMES [PDF]

open access: yes, 2013
Theoretical models suggest that chronic smoking may be associated with both hypersensitivity to smoking and related cues and hyposensitivity to alternative reinforcers, and that these effects may be more pronounced during deprivation from smoking ...
Sweitzer, Maggie
core  

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