Results 131 to 140 of about 147,438 (217)

Somatotopic functional connectivity gradients in the monkey and human striatum. [PDF]

Imaging Neurosci (Camb)
Goda N, Chiken S, Koketsu D, Nambu A, Fukunaga M.   +4 more
europepmc   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

Brain PDGFRβ⁺ Cells Exhibit Diverse Reactive Phenotypes After Stroke Without Requiring KLF4. [PDF]

Glia
Manrique-Castano D, ElAli A.
europepmc   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Inhibition of Striatal miR-141-3p Ameliorates Cognitive Deficits and Neuroinflammation in an ADHD Animal Model. [PDF]

Pharmaceuticals (Basel)
Chang TM, Chiu CC, Chen YC, Wen ZH, Hsu TC, Tzang BS.   +5 more
europepmc   +1 more source

Characterization of the Middle Ear Microbiome in Meniere's Disease by 16S rRNA Gene Sequencing Compared to Chronic Suppurative Otitis Media

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the middle ear microbiome in Meniere's disease (MD) patients. Methods Middle ear smears from 10 MD patients (ME group) and 10 chronic suppurative otitis patients (OE group) were collected during surgery and processed via 16S rRNA gene sequencing.
Yu‐Ting Tao, Lin Wang, Hong‐wei Zheng, Li‐Sheng Yu   +3 more
wiley   +1 more source

Sex differences in ferroptosis-related vulnerability to autism-like deficits in the adolescent medial prefrontal cortex following embryonic valproic acid exposure. [PDF]

Biol Sex Differ
Zhao S, Wang J, Pan Y, Yang Y, Yin Y, Li W, Li J, Feng X.   +7 more
europepmc   +1 more source

Spatial patterns of amyloid clearance after donanemab: A preliminary 12-month real-world amyloid PET study in Japanese patients with early Alzheimer's disease. [PDF]

Alzheimers Dement (Amst)
Kujuro Y, Saito M, Maruko M, Qian E, Koh H, Katai H, Hattori H.   +6 more
europepmc   +1 more source

Chromatin Accessibility Profiling of the Canine Brain Reveals Regulatory Programs Associated With Dog‐Wolf Divergence and Human Psychiatric Risk

Integrative Zoology, EarlyView.
The dog is a valuable model for studying social behavior and neuropsychiatric disease. We generated an ATAC‐seq atlas of 7 brain regions and pituitary from 4 beagles, identifying 251,492 CREs. Integrating dog‐wolf divergence revealed tissue‐specific CREs overlapping divergent loci, including neuronal and neuroendocrine genes.
Biao Deng, Junze Wu, Ye Liu, Xuan Li, Yuanfang Xu, Rongjie Duan, Yibo Tong, Jinsheng Xu, Mengyang Ni, Zijie Scott Zhang, Dan Xue, Bowen Zhou, Yanhu Liu, Rui Cheng, Yuedong Zhang, Ya‐Ping Zhang   +15 more
wiley   +1 more source

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

Addiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien, Lisa‐Marie Greenwood, Arush Honnedevasthana Arun, Isabella Goodwin, Anastasia Paloubis, Tribikram Thapa Rana, Marianna Quinones Valera, Eugene McTavish, Gabrielle Abbott, Suraya Dunsford, Antonio Verdejo‐Garcia, Jessica Ramamurthy, Mark M. Schira, Nadia Solowij, Chao Suo, Valentina Lorenzetti   +15 more
wiley   +1 more source