Movement Disorders Clinical Practice, EarlyView.Abstract Background The Movement Disorder Society‐Unified Parkinson's Disease Rating Scale‐Part III (MDS‐UPDRS‐III) is subjective and insensitive to subtle changes in patients with Parkinson's disease (PD). Computer vision (CV) can extract objective kinematics from routine outpatient videos, potentially augmenting the accuracy of the motor assessment ...
Pasquale Maria Pecoraro +12 more
wiley +1 more source
Role of fast-spiking interneurons in modulating across-trial variability and within-trial correlations in the striatum. [PDF]
PLoS Comput BiolGuo L, Kumar A.
europepmc +1 more source
Striosome-Like Structural Connectivity Is Reduced in the Rostral Putamen in Anxiety Disorder. [PDF]
Depress AnxietyFunk AT, Waugh JL.
europepmc +1 more source
Longitudinal Videofluorographic Dysphagia Measures in Progressive Supranuclear Palsy
Movement Disorders Clinical Practice, EarlyView.Abstract Background Dysphagia can lead to fatal aspiration pneumonia in progressive supranuclear palsy (PSP). Little is known about the longitudinal progression of dysphagia or whether it differs across PSP clinical variants. Objectives To characterize longitudinal changes in dysphagia across PSP variants and determine relationships with disease ...
Anna Chiara Cattani +8 more
wiley +1 more source
Synchronous activation of striatal cholinergic interneurons induces local serotonin release. [PDF]
Nat CommunMatityahu L +6 more
europepmc +1 more source
Brain Alterations Linked to the MPTP Mouse Model of Parkinson's Disease Uncovered by Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy. [PDF]
CNS Neurosci TherModi A +10 more
europepmc +1 more source
Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch +4 more
wiley +1 more source
Tyrosine Hydroxylase Deficiency Impairs TH Axonal Transport, Brain Function, and Neuronal Plasticity. [PDF]
J Inherit Metab DisShi TS +6 more
europepmc +1 more source
Movement Disorders, EarlyView.Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker +30 more
wiley +1 more source
The Neuroameliorative Effects of Enzymatically Modified Isoquercitrin and Sodium R-lipoate on the Rotenone rat Model of Parkinson's Disease. [PDF]
Neurochem ResHassouna I +3 more
europepmc +1 more source