Results 171 to 180 of about 264,556 (306)

Psychiatric Disorders and Apathy in Mixed Movement Disorders Linked to ADCY5 (MxMD‐ADCY5)

Movement Disorders, EarlyView.
Abstract Background Mixed movement disorders linked to ADCY5 (MxMD‐ADCY5) represent a rare hyperkinetic movement disorder resulting from pathogenic variants in ADCY5. Psychiatric symptoms are suspected to be part of the phenotype. Objective The study aim was to assess psychiatric comorbidities in patients with MxMD‐ADCY5.
Aurélie Méneret, Clément Tarrano, Asya Ekmen, Diane Doummar, Victoria Gonzalez, Christine Tranchant, Mathieu Anheim, Philippe Damier, Eoin Mulroy, Kailash P. Bhatia, Laura Cif, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Florence Riant, Manon Gomes, Vanessa Brochard, Agathe Roubertie, Oriane Trouillard, Caroline Dubacq, Yulia Worbe, Mohamed Doulazmi, Emmanuel Roze   +23 more
wiley   +1 more source

Antipsychotic effects of aqueous lyophilisate of <i>Ficus mucuso</i> on ketamine-induced schizophrenia. [PDF]

Front Neurol
Okomolo Moto FC, Diapa Tchiengang J, Kameni Njapdounke JS, Mbom A, Mbeboh Savo F, Aren Arsa'a MN, Nezoumne FN, Ndjock SR, Bum EN.   +8 more
europepmc   +1 more source

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo, Nagore Hernández‐Pinedo, Josefa Zaldivar‐Diez, Isabel Pérez‐Santos, José A. Obeso, Carmen Cavada, Javier Blesa   +6 more
wiley   +1 more source

Corpus striatum

, 2009
Jeremy Jones, Francis Deng, Craig Hacking   +2 more
  +4 more sources

Roflumilast Elicits Therapeutic and Neuroprotective Effects in 3-Nitropropionic Acid-Induced Huntington's Disease-Like Neurodegeneration in Rats by Mitigating NLRP3 Inflammasome-Mediated Pyroptosis, Ferroptosis, and Glial Activation. [PDF]

Neurochem Res
Taha M, Salah D, Abdou K, Senousy MA.
europepmc   +1 more source

In Vivo Mapping of Catecholaminergic Loss and Iron Deposition in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background The pathophysiology of Huntington's disease (HD) remains obscure. Magnetic resonance imaging (MRI) can reveal in vivo molecular changes related to disease pathology. Objectives To investigate catecholaminergic neuronal integrity and subcortical brain iron accumulation in HD employing neuromelanin‐sensitive MRI, and quantitative ...
Edoardo R. de Natale, Heather Wilson, Efstratios Karavasilis, Athanasia Liozidou, Chrisoula Kartanou, Georgios Velonakis, Jens Kuhle, Ioannis Zalonis, Georgia Karadima, Leonidas Stefanis, Georgios Koutsis, Marios Politis   +11 more
wiley   +1 more source

Estradiol, Emotion Regulation, and the Limbic System: Effects on Gray Matter Volume. [PDF]

Biol Psychiatry Glob Open Sci
Denninger AF, Rehbein E, Sundström-Poromaa I, Derntl B, Kogler L.   +4 more
europepmc   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

Prenatal valproate exposure alters midbrain and striatal neuronal morphology along with dopamine levels. [PDF]

Brain Struct Funct
Bugar Bodorova B, Havranek T, Mihalj D, Kupkova K, Bogyova E, Falougy HE, Bacova Z, Bakos J.   +7 more
europepmc   +1 more source

The Brain‐Age Gap in Pediatric Dystonia: Neuroanatomical Deviations Inform Deep Brain Stimulation Outcomes

Movement Disorders, EarlyView.
Abstract Background Dystonia in children is a heterogeneous condition with variable response to deep brain stimulation (DBS). Brain‐age gap, a machine learning‐derived metric of structural deviation from norm, may capture signatures that differentiate underlying biotypes and predict outcomes.
Timur H. Latypov, Alexandre Berger, Manuela Mohareb, Karim Mithani, Sara Breitbart, Lindsey M. Vogt, Thiemo Dinger, Inge Meijer, Alexander G. Weil, Alfonso Fasano, Carolina Gorodetsky, George M. Ibrahim   +11 more
wiley   +1 more source