Results 321 to 330 of about 325,395 (379)

Preferential superficial cortical layer activation during seizure propagation

Epilepsia, Volume 66, Issue 3, Page 929-941, March 2025.
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya, Shinnosuke Shiono, Chengsan Sun, Edward Perez‐Reyes, Jaideep Kapur   +4 more
wiley   +1 more source

Baseline physical activity moderates brain-behaviour relationships in response to framed health messages. [PDF]

Soc Cogn Affect Neurosci
Ahn J, Cooper N, Kang Y, O'Donnell MB, Green MA, Notthoff N, Carstensen LL, Samanez-Larkin GR, Falk EB.   +8 more
europepmc   +1 more source

Deep brain stimulation of the centromedian nucleus for drug‐resistant epilepsy in children: Quality‐of‐life and functional outcomes from the CHILD‐DBS registry

Epilepsia, EarlyView.
Abstract Objective Deep brain stimulation of the centromedian nucleus of the thalamus (CM‐DBS) is an investigational, off‐label treatment for drug‐resistant epilepsy (DRE) in children. Although emerging evidence supports its safety and efficacy for select indications, the effect of CM‐DBS on quality of life and functional outcomes such as school ...
Karim Mithani, Farbod Niazi, Hrishikesh Suresh, Yousof Alrumayyan, Eriberto R. Rayco, Ayako Ochi, Hiroshi Otsubo, Elizabeth Kerr, Sara Breitbart, Andrea LeBlanc‐Millar, Nisha Gadgil, Jeffrey S. Raskin, Alexander G. Weil, Aristides Hadjinicolaou, Christian Iorio‐Morin, Shelly Weiss, Puneet Jain, Lauren Sham, Elizabeth Donner, Alfonso Fasano, Carolina Gorodetsky, George M. Ibrahim   +21 more
wiley   +1 more source

Butyrate improves abnormal sleep architecture in a Parkinson's disease mouse model via BDNF/TrkB signaling. [PDF]

NPJ Parkinsons Dis
Duan WX, Xie WY, Ying C, Fen W, Cheng XY, Mao CJ, Liu JY, Liu CF.   +7 more
europepmc   +1 more source

Prevalence, clinical characteristics, and risk factors for psychosis in people with epilepsy: A multicenter retrospective cohort study

Epilepsia, EarlyView.
Abstract Objective We aimed to assess the prevalence, clinical characteristics, and risk factors for psychosis in a cohort of people with epilepsy in West China. Methods We used retrospective information from databases of three tertiary epilepsy centers, which included follow‐up records from 2006 onward.
Sisi Shen, Hanlin Sun, Zaiquan Dong, Tong Yi, Josemir W. Sander, Dong Zhou, Jinmei Li   +6 more
wiley   +1 more source

Absolute Number of Thalamic Parafascicular and Striatal Cholinergic Neurons, and the Three-Dimensional Spatial Array of Striatal Cholinergic Neurons, in the Sprague-Dawley Rat. [PDF]

J Comp Neurol
Zhang R, Wickens JR, Carrasco A, Oorschot DE.   +3 more
europepmc   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

The striatum is an early, accurate indicator of amyloid burden using [¹¹C]PiB in Down syndrome: Comparison of two radiotracers. [PDF]

Alzheimers Dement
McLachlan M, Bettcher B, McVea A, DiFilippo A, Zammit M, LeMerise L, Rouanet J, Price J, Tudorascu D, Laymon C, Keator D, Lao P, Brickman AM, Fryer T, Hartley S, Ances BM, Rosas HD, Johnson S, Betthauser T, Stone CK, Zaman S, Handen B, Head E, Mapstone M, Christian BT, Investigators AD.   +25 more
europepmc   +1 more source

d‐amino acids: new functional insights

The FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni, Natasa Kustrimovic, Luciano Piubelli, Elena Rosini, Valentina Rabattoni, Silvia Sacchi   +5 more
wiley   +1 more source

Divergent Longitudinal Trajectories and Neurotransmitter Associations of Striatal Subparcellation Spontaneous Activity in Major Depressive Disorder. [PDF]

Biol Psychiatry Glob Open Sci
Zang Z, Qiao K, Chen X, Zhou JJ, Yang Z, Wang G.   +5 more
europepmc   +1 more source