Results 331 to 340 of about 325,395 (379)

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source

Dual Role of Exosomes in Parkinson's Disease: Adenine Exerts a Beneficial Effect. [PDF]

CNS Neurosci Ther
Chen L, Shao YT, Geng J, Liu H, Liu QS, Cheng Y, Sun T.   +6 more
europepmc   +1 more source

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

Striatal functional connectivity associated with Sahaja Yoga meditation. [PDF]

Sci Rep
Perez-Diaz O, Hernández SE, Brown LL, Xiao Y, González-Mora JL, Rubia K, Barros-Loscertales A.   +6 more
europepmc   +1 more source

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader, Amy S. Garrett, Steven R. Pliszka   +2 more
wiley   +1 more source

Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity. [PDF]

Front Pharmacol
Hakopian E, Stepanian AE, Zhong S, Agyeman KA, Zepeda N, Wu K, Liu C, Lee DJ, Christopoulos V.   +8 more
europepmc   +1 more source

Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

Journal of Neuroendocrinology, EarlyView.
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez, Lei Cheng, Qing Chang, Paul E. Gold, Diego Perez‐Tilve, YanYan Wang   +5 more
wiley   +1 more source

Regional cerebral blood flow in a patient with restless legs syndrome exhibiting pramipexole-induced hypersexuality. [PDF]

PCN Rep
Obata T, Kobayashi R, Shirata T, Noto K, Sugai Y, Aboshi G, Kanoto M, Suzuki A.   +7 more
europepmc   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source