Results 31 to 40 of about 1,258,054 (362)

A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T Cell proliferation and anti-tumor immunity in mice

open access: yesNature Communications
Current antibody-based immunotherapy depends on tumor antigen shedding for proper T cell priming. Here we select a novel human CD40 agonistic drug candidate and generate a bispecific antibody, herein named BiA9*2_HF, that allows for rapid antibody ...
Aman Mebrahtu   +14 more
doaj   +1 more source

THE WORKFORCE OF HERZEGOVINA AND ITS INCLUSION IN THE PROCESS OF CROATIAN NATIONAL INTEGRATION [PDF]

open access: yesHum, 2013
With the arrival of Austrian-Hungarian monarchy in Bosnia and Herzegovina, transportation infrastructure and communications between settlements started to flourish.
Tihomir Zovko
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sergei Eisenstein in the Proletkult

open access: yesCultural Science, 2021
This article examines some of the theoretical issues that exercised Sergei Eisenstein during the years 1920–1924 when he worked in the Russian Proletarian Cultural-Educational Organization (Proletkult), of which Aleksandr Bogdanov was one of the founders.
Biggart John, Bulgakowa Oksana
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Streik ved Kongsvinger stasjon i 1920: Den lokale streikekomiteens perspektiver

open access: yesHeimen
Den 1. desember 1920 la de lokale jernbaneansatte ved Kongsvinger stasjon ned arbeidet. Jernbanestreiken var landsomfattende. I denne artikkelen undersøker jeg streiken lokalt på Kongsvinger stasjon med utgangspunkt i primærkildene etter streikeleder ...
Inga Lill Grønnerud
doaj   +1 more source

FORMATION OF FACTORY LEGISLATION IN THE FIELD OF COLLECTIVE LABOR DISPUTES RESOLUTION

open access: yesГуманитарные и юридические исследования, 2021
The historical aspect of the study of the problems of settlement of collective labor disputes in Russia deserves closer attention, including through the prism of modern problems of legal regulation of relations in the field of labor.
T. Vysheslavova
doaj  

The Right to Strike by Medical Practitioners

open access: yesStudia Iuridica Lublinensia, 2020
The right to strike action is one of the fundamental human rights and trade union freedoms. Strike, as a form of protest against broadly understood injustice is one of the most important measures of trade union protection of workers’ interests.
Anna Daniluk-Jarmoniuk
doaj   +1 more source

Running Injuries Due to Strike Patterns [PDF]

open access: yes, 2017
Running is a very repetitive activity that can lead to surmountable stresses to the body over time that could lead to injury. Running biomechanics can influence the effects that the body will experience.
Rogers, Jamie M
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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