Results 31 to 40 of about 579,196 (311)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Les plans d’austérité imposés à la Grèce : impact sur les droits sociaux et syndicaux et réactions syndicales

open access: yesRevue Interventions Économiques, 2015
The Greek public debt crisis has led to significant institutional and political changes, leading to an almost total disruption of the context in which unions act and changing the power relations within industrial relations. Thus, the Greek unions are now
Christina Karakioulafis
doaj   +1 more source

The Composition of Strike Activity in the Construction Industry [PDF]

open access: yes, 1976
This study shows that strikes in construction have, by most measures, increased during the years since 1949, a period during which strike activity tended to decline in American industry as a whole.
Farber, Henry S, Lipsky, David B
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

La jornada de reconciliación nacional del 5 de mayo de 1958

open access: yesEspacio, Tiempo y Forma. Serie V, Historia Contemporánea, 2008
En la segunda mitad de la década de los cincuenta la dictadura franquista atravesaba un período de crisis, ante la gravedad de la situación socio-económica que atravesaba el país, es en este contexto en el que el Partido Comunista de España decidió ...
Félix Hernández
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

O ciclo de agitação social global de 1917-1920

open access: yesLer História, 2014
This article focuses on the cycle of social unrest of late First World War and its crucial role in widening and politicizing the workers’ movement. Based on empirical evidences on the Portuguese case and recent literature, it will be argued that new and ...
Joana Dias Pereira
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Mobilising the Masses: Explaining the Rapid Rise of Worker Activism in Transnistria in the Late 1980s

open access: yesComparative Southeast European Studies, 2023
Between August and September 1989, Russian-speaking workers in Moldova went on strike against a series of laws that made Moldovan the sole official language of the republic.
Harrington Keith
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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