Results 101 to 110 of about 2,071 (267)
Advanced Science, EarlyView.Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Journal of High Energy PhysicsWe derive and test a novel holographic duality in the B-model topological string theory. The duality relates the B-model on certain Calabi-Yau three-folds to two-dimensional chiral algebras defined as gauged βγ systems. The duality conjecturally captures
Kevin Costello, Davide Gaiotto
doaj +1 more source
Cusp anomalous dimension and rotating open strings in AdS/CFT
Journal of High Energy Physics, 2018 In the context of AdS/CFT we provide analytical support for the proposed duality between a Wilson loop with a cusp, the cusp anomalous dimension, and the meson model constructed from a rotating open string with high angular momentum.
R. Espíndola, J. Antonio García
doaj +1 more source
Advanced Science, EarlyView.Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang +14 more
wiley +1 more source
String free energy, Hagedorn and gauge/string duality [PDF]
Journal of High Energy Physics, 2009 We give examples of modeling the string free energy whose behavior mimics that of QCD: a power-law at high temperature and an exponential decrease at low temperature. Although the effective description is in terms of strings, no limiting temperature exists, as expected for a crossover.
openaire +2 more sources
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Advanced Science, EarlyView.Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
N = 2 String-String Duality and Holomorphic Couplings [PDF]
Fortschritte der Physik, 1998 86 pages ...
openaire +2 more sources
Advanced Science, EarlyView.Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma +10 more
wiley +1 more source
Electric-magnetic duality in string theory [PDF]
Nuclear Physics B, 1993 20 pages, phyzzx.tex, TIFR-TH-92-41 (The section on dyonic black holes has been modified and expanded, minor corrections have been made in the other sections)
openaire +2 more sources
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source