Results 161 to 170 of about 96,015 (345)

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

JT gravity from non-Abelian T-duality

open access: yesJournal of High Energy Physics
We study the geometries obtained by performing super non-Abelian T-duality of the Principal Chiral Model on OSp(1|2). While the initial model represents an appropriate 3D supergravity background, interpretable as the superspace version of AdS3, the T ...
Daniele Bielli   +2 more
doaj   +1 more source

A microscopic realization of dS$_3$

open access: yesSciPost Physics
We propose a precise duality between pure de Sitter quantum gravity in $2+1$ dimensions and a double-scaled matrix integral. This duality unfolds in two distinct aspects.
Scott Collier, Lorenz Eberhardt, Beatrix Mühlmann
doaj   +1 more source

d‐Wave Fermi Surface Instability in the Nematic Phase of Two Monolayer FeSe/SrTiO3

open access: yesAdvanced Science, EarlyView.
Angle‐resolved photoemission spectroscopy reveals a d‐wave nematic order in two‐monolayer FeSe/SrTiO3, showing degenerate dxz/dyz bands at Γ but a pronounced splitting at M. This momentum‐dependent anisotropy identifies the nematicity as a d‐wave Fermi surface (Pomeranchuk) instability, highlighting 2D FeSe as a model platform to explore the interplay ...
C. Y. Tang   +14 more
wiley   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Exact duality in the string effective action [PDF]

open access: green, 1994
Eric Bergshoeff   +2 more
openalex   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

M-theory and a Topological String Duality [PDF]

open access: green, 2006
Robbert Dijkgraaf   +2 more
openalex   +1 more source

Thermo‐Responsive Self‐Recoverable Porous Sensors with Writable Electrodes: Advancing Wearable Motion Detection

open access: yesAdvanced Science, EarlyView.
A self‐recoverable flexible porous sensor with diverse designability of electrodes is developed through writable vapor phase polymerization using shape memory polymers (SMPs) as the fundamental materials. The sensors enable long‐term comprehensive human motion detection.
Ying Gao   +7 more
wiley   +1 more source

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