Results 181 to 190 of about 96,015 (345)

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

open access: yesAdvanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma   +10 more
wiley   +1 more source

Geodesic completeness from string T-duality

open access: yesEuropean Physical Journal C: Particles and Fields
By studying the Raychaudhuri equation for the gravitational force resulting from a string T-duality modified propagator, we present an analysis of the geodesic compression beyond the conventional classical limit.
Kimet Jusufi, Piero Nicolini
doaj   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

open access: yesAdvanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang   +10 more
wiley   +1 more source

String duality and massless string states

open access: yes, 1995
We are discussing the $S$ \& $T$ duality for special class of heterotic string configurations. This class of solutions includes various types of black hole solutions and Taub-NUT geometries. It allows a self-dual point for both dualities which corresponds to massless configurations.
openaire   +2 more sources

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

M-Theory and String-String Duality

open access: yes, 1996
In this article we examine the compatibility of some recent results, results relating M-Theory to String Theory, with the string-string duality conjecture in six-dimensions. In particular, we rederive the relation between M-Theory and Type IIA strings.
openaire   +2 more sources

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