Results 151 to 160 of about 6,660,767 (299)

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

On non-BPS effective actions of string theory. [PDF]

open access: yesEur Phys J C Part Fields, 2018
Hatefi E.
europepmc   +1 more source

SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
This study highlights the capacity for tumor suppressor SATB2 to recruit HDAC3 and catalyze histone H3K9 delactylation, thereby repress transcription of the oncogene LCN2. This novel epigenetic‐metabolic axis inhibits the growth and metastasis of non‐small cell lung cancer, delineating a new mechanistic pathway with potential therapeutic relevance ...
Ting Wen   +10 more
wiley   +1 more source

Light and compressed gluinos at the LHC via string theory. [PDF]

open access: yesEur Phys J C Part Fields, 2017
AbdusSalam SS.
europepmc   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

open access: yesAdvanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang   +15 more
wiley   +1 more source

New Janus interfaces from four-dimensional $$N=3$$ N = 3 gauged supergravity

open access: yesEuropean Physical Journal C: Particles and Fields
We construct new supersymmetric Janus solutions from four-dimensional $$N=3$$ N = 3 gauged supergravity coupled to eight vector multiplets with $$SO(3)\times SU(3)$$ S O ( 3 ) × S U ( 3 ) gauge group.
Parinya Karndumri
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Twisted compactifications and conformal defects from ISO(3) $$\times $$ × U(1) F(4) gauged supergravity

open access: yesEuropean Physical Journal C: Particles and Fields
We study holographic solutions describing RG flows across dimensions from five-dimensional $$N=2$$ N = 2 SCFT to SCFTs in three and two dimensions using matter-coupled F(4) gauged supergravity with $$ISO(3)\times U(1)$$ I S O ( 3 ) × U ( 1 ) gauge group.
Parinya Karndumri
doaj   +1 more source

Machine Learning for Designing Perovskites and Perovskite‐Inspired Solar Materials: Emerging Opportunities and Challenges

open access: yesAdvanced Science, EarlyView.
This review offers a comprehensive comparison between perovskites and perovskite‐inspired materials (PIMs), focusing on their crystal structures, electronic properties, and chemical compositions. It evaluates the applicability of machine learning (ML) descriptors and models across both material classes.
Yangfan Zhang   +6 more
wiley   +1 more source

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