Results 91 to 100 of about 18,552 (304)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Semiclassical dynamics for torsional Newton-Cartan strings

open access: yesNuclear Physics B, 2020
We explore folded spinning string configurations over torsional Newton Cartan (TNC) geometry with R×S2 topology within the semiclassical approximation. We consider the large c and/or nonrelativistic (NR) limit associated with the world-sheet d.o.f.
Dibakar Roychowdhury
doaj   +1 more source

ON THE GENUS EXPANSION IN THE TOPOLOGICAL STRING THEORY [PDF]

open access: yesReviews in Mathematical Physics, 1995
A systematic formulation of the higher genus expansion in topological string theory is considered. We also develop a simple way of evaluating genus zero correlation functions. At higher genera we derive some interesting formulas for the free energy in the A1 and A2 models.
Eguchi, Tohru   +2 more
openaire   +3 more sources

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Deformation of String Topology into Homotopy Skein Modules [PDF]

open access: yes, 2003
Relations between the string topology of Chas and Sullivan and the homotopy skein modules of Hoste and Przytycki are studied. This provides new insight into the structure of homotopy skein modules and their meaning in the framework of quantum topology ...
Kaiser, Uwe
core   +2 more sources

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Cosmic necklaces in string theory and field theory [PDF]

open access: yes, 2010
PhDIn this thesis we investigate astrophysical phenomena which arise in models with compact extra dimensions, focussing on the cosmological consequences of strings which wrap cycles in the internal space. Embedding our strings in the Klebanov-Strassler
Lake, Matthew James
core  

Topology, rigid cosymmetries and linearization instability in higher gauge theories [PDF]

open access: yes, 2015
We consider a class of non-linear PDE systems, whose equations possess Noether identities (the equations are redundant), including non-variational systems (not coming from Lagrangian field theories), where Noether identities and infinitesimal gauge ...
Sub String Theory Cosmology and ElemPart   +2 more
core   +1 more source

Neutrino zeromodes on electroweak strings in light of topological insulators

open access: yesJournal of High Energy Physics
We examine neutrino zeromode solutions on the electroweak Z-string and their effect on the stability of the string in the standard model and its extensions.
Minoru Eto   +4 more
doaj   +1 more source

Tetrahedral modular graph functions

open access: yesJournal of High Energy Physics, 2017
The low-energy expansion of one-loop amplitudes in type II string theory generates a series of world-sheet integrals whose integrands can be represented by world-sheet Feynman diagrams.
Axel Kleinschmidt, Valentin Verschinin
doaj   +1 more source

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