Results 91 to 100 of about 5,540,038 (306)

Suspect MELAS early to prevent unnecessary costs and burdens for the affected

Radiology Case Reports, 2021
Josef Finsterer, MD, PhD
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Effect of Pre-nutrion of Flax Seed Oil (Linum Usitatissimum) on the amount of Cerebral ischemic lesion and motor nerve disorders in animal model rat.

Armaghane Danesh Bimonthly Journal, 2015
Background & aim: Stroke is the third death agent (factor) in industrial countries after cardiovascular disease and cancer. With regard to high content of antioxidant materials in flax seed oil like &alpha-linolenic acid, lignan as well as phenolic ...
SV Hosseini, Mehdi Rahnema, Mohammad Reza Bigdeli   +2 more
doaj  

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Preparing for a Second Attack: A Lesion Simulation Study on Network Resilience After Stroke

, 2022
Background: Does the brain become more resilient after a first stroke to reduce the consequences of a new lesion? Although recurrent strokes are a major clinical issue, whether and how the brain prepares for a second attack is unknown. This is due to the
Julian Klug, Van Assche, Mitsouko, Elisabeth Dirren, Dirren, Elisabeth, Jonas Richiardi, Klug, Julian, Mitsouko van Assche, Carrera, Emmanuel, Emmanuel Carrera, Richiardi, Jonas, Carrera, E., van Assche, M., Klug, J., Dirren, E., Richiardi, J.   +14 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Cerebral Hyper-perfusion in Stroke-like Lesions may be Secondary and not Pathogenic

Journal of Clinical Cases & Reports, 2018
In a recent article, a study of cerebral perfusion in 20 patients with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) by MRI/MRA was presented. We have the following comments/concerns.
Finsterer Josef, Zarrouk-Mahjoub Sinda
openaire   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

The Royal Blackburn Hospital, Acute Stroke Unit [PDF]

Stroke Unit ...
Ramsden, Victoria, Philip, Sheeba J.
core   +1 more source

Within-lesion heterogeneity of subcortical DWI lesion evolution, and stroke outcome: A voxel-based analysis [PDF]

, 2019
The fate of subcortical diffusion-weighted imaging (DWI) lesions in stroke patients is highly variable, ranging from complete tissue loss to no visible lesion on follow-up.
Bayer-Karpinska, Anna, Caballero, Miguel A. Araque, Duering, Marco, Adam, Ruth, Stöcklein, Sophia, Pasternak, Ofer, Baykara, Ebru, Wollenweber, Frank A., Cubillos-Pinilla, Leidy Y., Gesierich, Benno, Ewers, Michael, Dichgans, Martin   +11 more
core   +1 more source