Results 91 to 100 of about 94,076 (308)

Early results of stroke-like supratentorial tumors surgical treatment

Ендоваскулярна нейрорентгенохірургія, 2017
Objective – to study early results of surgical treatment in 176 patients with supratentorial tumors (ST) with a stroke-like course. Materials and methods. The results of surgical treatment of 176 patients with stroke-like tumors were studied.
O.M. Goncharuk, A.A. Oblyvach, Y.Yu. Freidman, A.O. Kaminskiy, T.I. Makeeva   +4 more
doaj   +1 more source

Cerebral Hyper-perfusion in Stroke-like Lesions may be Secondary and not Pathogenic

Journal of Clinical Cases & Reports, 2018
In a recent article, a study of cerebral perfusion in 20 patients with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) by MRI/MRA was presented. We have the following comments/concerns.
Finsterer Josef, Zarrouk-Mahjoub Sinda
openaire   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Is Troponin really a reliable marker in patients with acute ischemic stroke?

Romanian Journal of Internal Medicine, 2018
Background and purpose. Cardiac troponin I (cTnI) is a reliable marker to diagnose acute myocardial infarction, but the pathophysiological explanation for the increase in cTnI levels in patients with acute ischemic stroke (IS) remains unknown.
Yildiz Zeynep, Koçer Abdulkadir, Avşar Şahin, Cinier Göksel   +3 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Spatial neglect after subcortical stroke may reflect cortico-cortical disconnection

Scientific Reports
Spatial neglect is commonly attributed to lesions of a predominantly right-hemispheric cortical network. Although spatial neglect was also repeatedly observed after lesions to the basal ganglia and the thalamus, many anatomical network models omit these ...
Christoph Sperber, Hannah Rosenzopf, Max Wawrzyniak, Julian Klingbeil, Dorothee Saur, Hans-Otto Karnath   +5 more
doaj   +1 more source

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC

, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian, Waltraud Pfeilschifter, Daniel Spitzer, Pfeilschifter, Josef (Prof. Dr.), Helmuth Steinmetz, Spitzer, Daniel, Steinmetz, Helmuth, Steinmetz Helmuth, Christian Foerch, Pfeilschifter, Waltraud, Josef Pfeilschifter, Pfeilschifter Waltraud, Spitzer Daniel, Foerch Christian, Pfeilschifter Josef   +14 more
core   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Matrix metalloproteinases at key junctions in the pathomechanism of stroke

, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Kolev, Kraszimir, Kolev Krasimir, Rottenberger Zsolt, Zsolt Rottenberger, Rottenberger, Zsolt, Krasimir Kolev   +5 more
core   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source