Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS
Brain and Development, 2013Hypoperfusion on single-photon emission computed tomography (SPECT) of the stroke-like lesion (SLL) at the hyperacute stage of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) is considered to be a supportive evidence of the mitochondrial angiopathy theory.
Hsu-Ling, Yeh +6 more
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No evidence of ischemia in stroke-like lesions of mitochondrial POLG encephalopathy
Mitochondrion, 2017Stroke-like lesions are characteristically associated with mitochondrial encephalopathies such as those caused by mutations of polymerase gamma (POLG) and the m.3243A>G mitochondrial DNA (mtDNA) mutation. The combination of acute clinical onset, MRI and pathological abnormalities, have led to the suggestion that these lesions are ischemic.
Charalampos Tzoulis +3 more
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Choriocarcinoma with cerebral metastasis presenting as a stroke-like lesion
Sahel Medical Journal, 2015Choriocarcinoma is a very aggressive malignant variant of gestational trophoblastic disease characterized by malignant proliferation of trophoblastic tissues and absence of chorionic villi. We present a rare case of metastatic choriocarcinoma presenting with a stroke-like lesion. A 40-year old multiparous woman that presented with bleeding per vaginam,
CNnadi Daniel, IG Ango, EI Nwobodo
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Regression of stroke‐like lesions in MELAS‐syndrome after seizure control
Epileptic Disorders, 2010ABSTRACTThere are some indications that seizure activity promotes the development of stroke‐like episodes, or vice versa, in patients with mitochondrial encephalopathy, lactic acidosis and stroke‐like episodes (MELAS) syndrome or other syndromic mitochondrial disorders.
Josef, Finsterer, Peter, Barton
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Accumulation of oxidative stress around the stroke-like lesions of MELAS patients
Mitochondrion, 2009To investigate the relationship between oxidative stress and progressive spread of the stroke-like lesions in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with 3243A>G mutation, we retrospectively analyzed the spread frequency in patients with and without treatment with the radical scavenger edaravone ...
Yuri, Katayama +7 more
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Reagibility of Intracerebral Arteries May Not Reflect Dynamics of a Stroke-Like Lesion
IAR-Medical Series, 2021With interest we read the review article by Gramegna et al. about the involvement of cerebral vessels in mitochondrial encephalopathy, lactic acidosis, and stroke-like episode (MELAS) syndrome [1]. Among 46 MELAS patients reported in 23 papers dilatation of the major cerebral vessels was found in 37% (in 88% of them during a stroke-like lesion (SLL ...
Finsterer J., Fulvio A. Scorza
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Exclude herpes simplex encephalitis as a differential of stroke-like lesions
Himalayan Journal of Applied Medical Sciences and Research, 2021With interest we read the article by Chen about a 52yo female with diabetes and end-stage renal disease (ESRD), requiring hemodialysis, who experienced sudden onset fever, delir, elevated lactate, and epilepsy being initially diagnosed as herpes simplex encephalitis (HSE) [1].
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Transient ischemic attack-like episodes without stroke-like lesions in MELAS
Pediatric Radiology, 2013A stroke-like episode is a core symptom in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Proton magnetic resonance spectroscopy (1H-MRS) is useful in the diagnosis of mitochondrial diseases. We report an 8-year-old girl with MELAS, presenting with a seizure and blindness.
Tadahiro, Mitani +4 more
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Stroke‐like episodes and stroke‐like lesions: Two aspects of the same phenomenon
European Journal of Neurology, 2023Josef Finsterer, Sounira Mehri
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Reply to “Cortical cystic lesions – A typical endpoint of a stroke-like lesion”
Brain and Development, 2021Noriko, Sato, Hidetoshi, Ishigaki
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