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Characteristics of stroke-like lesions on cerebral imaging
Ideggyógyászati szemle, 2023Objective – Stroke-like lesions (SLLs) are pathognomonic for mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome but occur in other mitochondrial and non-mitochondrial disorders as well. This mini-review aims at summarising and discussing recent findings to open up future perspectives how to manage this fleeting ...
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Metabolic stroke or stroke-like lesion: Peculiarities of a phenomenon
Journal of the Neurological Sciences, 2020One of the most frequent cerebral lesions in mitochondrial disorders(MIDs) on imaging is the stroke-like lesion(SLL) clinically manifesting as stroke-like episode (SLE, metabolic stroke). This review aims at discussing recent advances concerning the presentation, diagnosis, and treatment of SLLs.Systematic literature review using appropriate search ...
Josef Finsterer, Rahim Aliyev
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Knowledge about the characteristics of stroke-like lesions is expandable
Metabolic Brain Disease, 2021Stroke-like episodes (SLEs) are a common phenotypic feature of various syndromic and non-syndromic mitochondrial disorders (MIDs), particularly of mitochondrial encephalopathy, lactic acidosis, and stroke-like episode syndrome (MELAS). The morphological equivalent of a SLE is the stroke-like lesion (SLE), a dynamic lesion, which initially expands to ...
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Slowly progressive spread of the stroke-like lesions in MELAS
Neurology, 2003Little is known about temporal and spatial progression of the stroke-like lesion during the acute stage of the stroke-like episode in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).In four stroke-like episodes of MELAS observed in three patients, MRI, EEG, and SPECT were studied consecutively ...
Takahiro, Iizuka +3 more
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Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS
Brain and Development, 2013Hypoperfusion on single-photon emission computed tomography (SPECT) of the stroke-like lesion (SLL) at the hyperacute stage of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) is considered to be a supportive evidence of the mitochondrial angiopathy theory.
Hsu-Ling, Yeh +6 more
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No evidence of ischemia in stroke-like lesions of mitochondrial POLG encephalopathy
Mitochondrion, 2017Stroke-like lesions are characteristically associated with mitochondrial encephalopathies such as those caused by mutations of polymerase gamma (POLG) and the m.3243A>G mitochondrial DNA (mtDNA) mutation. The combination of acute clinical onset, MRI and pathological abnormalities, have led to the suggestion that these lesions are ischemic.
Charalampos Tzoulis +3 more
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Choriocarcinoma with cerebral metastasis presenting as a stroke-like lesion
Sahel Medical Journal, 2015Choriocarcinoma is a very aggressive malignant variant of gestational trophoblastic disease characterized by malignant proliferation of trophoblastic tissues and absence of chorionic villi. We present a rare case of metastatic choriocarcinoma presenting with a stroke-like lesion. A 40-year old multiparous woman that presented with bleeding per vaginam,
CNnadi Daniel, IG Ango, EI Nwobodo
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Reagibility of Intracerebral Arteries May Not Reflect Dynamics of a Stroke-Like Lesion
IAR-Medical Series, 2021With interest we read the review article by Gramegna et al. about the involvement of cerebral vessels in mitochondrial encephalopathy, lactic acidosis, and stroke-like episode (MELAS) syndrome [1]. Among 46 MELAS patients reported in 23 papers dilatation of the major cerebral vessels was found in 37% (in 88% of them during a stroke-like lesion (SLL ...
Finsterer J., Fulvio A. Scorza
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