Results 231 to 240 of about 94,076 (308)

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

open access: yesMovement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo   +10 more
wiley   +1 more source

A Sub‐Microsecond Switch Enabling SWIFT 23Na Imaging at 10.5 T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To enable sodium SWIFT imaging, which is a zero‐echo time imaging technique, at ultra‐high magnetic fields through the development of custom electronics hardware, and to showcase this capability with in vivo imaging results. Methods The custom hardware developed consists of a high‐speed optical trigger with 10 ns resolution, an in‐bore
Russell L. Lagore   +10 more
wiley   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

MRI in Sheep Model for Myelomeningocele Repair Using a Novel Polymer and Other Dural Patches

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To compare postnatal MRI outcomes after prenatal myelomeningocele repair using three different dural substitutes. Method 32 sheep fetuses were included, with 34.3%(11/32) serving as healthy controls and the remaining undergoing prenatal spinal lumbar defect creation to recreate a myelomeningocele in the fetus.
Usha D. Nagaraj   +5 more
wiley   +1 more source

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