Results 41 to 50 of about 5,540,038 (306)

The Impact of Cortical Lesions on Thalamo-Cortical Network Dynamics after Acute Ischaemic Stroke: A Combined Experimental and Theoretical Study. [PDF]

PLoS Computational Biology, 2016
The neocortex and thalamus provide a core substrate for perception, cognition, and action, and are interconnected through different direct and indirect pathways that maintain specific dynamics associated with functional states including wakefulness and ...
Joeri B G van Wijngaarden, Riccardo Zucca, Simon Finnigan, Paul F M J Verschure   +3 more
doaj   +1 more source

Stroke-like lesions in mitochondrial disease may resemble ischemic stroke

Journal of Family Medicine and Primary Care, 2021
The patient is a 73-y-male who was referred after a fall without losing consciousness or secessus. Clinical exam revealed disorientation, ophthalmoparesis, hemianopia to the left, left hemineglect, hypoacusis, quadruparesis, general wasting, generally reduced tendon reflexes, mild rigor, occasional myoclonic jerks of the right
openaire   +4 more sources

Transferrin-Enabled Blood–Brain Barrier Crossing Manganese-Based Nanozyme for Rebalancing the Reactive Oxygen Species Level in Ischemic Stroke

Pharmaceutics, 2022
(1) Background: Acute ischemic stroke (IS) is one of the main causes of human disability and death. Therefore, multifunctional nanosystems that effectively cross the blood–brain barrier (BBB) and efficiently eliminate reactive oxygen species (ROS) are ...
Qianqian Zhao, Wenxian Du, Lingling Zhou, Jianrong Wu, Xiaoxing Zhang, Xiaoer Wei, Sijia Wang, Yu Huang, Yuehua Li   +8 more
doaj   +1 more source

Tick-borne Encephalitis: Stroke-like Presentation

, 2019
Tick-borne encephalitis, caused by the tick-borne virus (TBEV), is endemic in central, eastern, and northern Europe eastwards through Russian Siberia and China. For the year 2009, the highest incidence in Scandinavian countries was in Sweden.
Lundin, Fredrik,, Eleftheriou, A, Petropoulos, EA, Lundin, F, Eleftheriou, Andreas,, Petropoulos, Evangelos Alexandros,   +5 more
core   +1 more source

FTY720 treatment in the convalescence period improves functional recovery and reduces reactive astrogliosis in photothrombotic stroke [PDF]

, 2013
Background: The Sphingosine-1-phosphate (S1P) signaling pathway is known to influence pathophysiological processes within the brain and the synthetic S1P analog FTY720 has been shown to provide neuroprotection in experimental models of acute stroke ...
Michel Mittelbronn, Alexander Koch (77280), Pia Zeiner (440015), Koch, Alexander, Mirceska, Ana, Ana Mirceska, Zeiner, Pia Susan, Michel Mittelbronn (307400), Alexander Koch, Derouiche, Amin, Helmuth Steinmetz (149409), Pfeilschifter, Josef, Nerea Ferreirós, Josef Pfeilschifter (92946), Kanaan, Nathalie, Amin Derouiche (226736), Mittelbronn, Michel Guy André, Christian Foerch (149410), Pia Zeiner, Ferreirós Bouzas, Nerea, Förch, Christian, Nathalie Kanaan, Waltraud Pfeilschifter, Robert Brunkhorst, Nathalie Kanaan (440013), Brunkhorst, Robert, Waltraud Pfeilschifter (149411), Helmuth Steinmetz, Steinmetz, Helmuth, Christian Foerch, Pfeilschifter, Waltraud, Josef Pfeilschifter, Robert Brunkhorst (405629), Ana Mirceska (149407), Amin Derouiche, Nerea Ferreirós (440014), Steinmetz Helmuth, Koch Alexander, Mittelbronn Michel, Ferreirós Nerea, Mirceska Ana, Zeiner Pia, Derouiche Amin, Pfeilschifter Waltraud, Kanaan Nathalie, Brunkhorst Robert, Foerch Christian, Pfeilschifter Josef   +47 more
core   +2 more sources

Determinants of post-stroke depression among stroke survivors at University of Gondar Hospital, Northwest Ethiopia: a case-control study

BMC Neurology, 2022
Background Stroke is one of the most common causes of disability among adults. Post-stroke depression (PSD) is a frequent neuropsychiatric complication in stroke patients. Despite the increasing prevalence of stroke, there is a paucity of data on PSD and
Ephrem Fantu, Workagegnehu Hailu, Nebiyu Bekele, Tewodros Tsegaye, Melaku Tadesse, Mezgebu Silamsaw Asres   +5 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury

Journal of Neuroinflammation, 2012
Background Using a live imaging approach, we have previously shown that microglia activation after stroke is characterized by marked and long-term induction of the Toll-like receptor (TLR) 2 biophotonic signals. However, the role of TLR2 (and potentially
Bohacek Ivan, Cordeau Pierre, Lalancette–Hébert Mélanie, Gorup Dunja, Weng Yuan-Cheng, Gajovic Srecko, Kriz Jasna   +6 more
doaj   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Associations between stroke severity, aphasia severity, lesion location, and lesion size in acute stroke, and aphasia severity one year post stroke [PDF]

, 2021
Background - The aim of the present study was to investigate the associations stroke severity, aphasia severity, lesion location and lesion size in acute stroke, and aphasia severity in the subacute and chronic stages post stroke.
Helland, Wenche Andersen, Næss, Halvor, Specht, Karsten, Helland, Turid, Hofstad, Håkon, Døli, Hedda, Karsten Specht, Wenche Andersen Helland, Turid Helland, Halvor Næss, Hedda Døli, Håkon Hofstad   +11 more
core   +1 more source