Brain lesion volume and capacity for consent in stroke trials: potential regulatory barriers to the use of surrogate markers [PDF]
, 2008 <p><b>Background and Purpose:</b> European directives and legislation in some countries forbid inclusion of subjects incapable of consent in research if recruitment of patients capable of consent will yield similar results.
Muir, K.W. +5 more
core +1 more source
Antioxidant status in acute stroke patients and patients at stroke risk [PDF]
, 2004 Background and Purpose: Antioxidant enzymes like copper/ zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular ...
Haberl, R. L. +9 more
core +1 more source
The prognosis of allocentric and egocentric neglect : evidence from clinical scans [PDF]
, 2012 We contrasted the neuroanatomical substrates of sub-acute and chronic visuospatial deficits associated with different aspects of unilateral neglect using computed tomography scans acquired as part of routine clinical diagnosis.
Chechlacz, Magdalena +34 more
core +1 more source
Animal models for investigating post-stroke cognitive impairment: A neurovascular trafficking perspective. [PDF]
Animal Model Exp MedAnimal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Kaewkaen P.
europepmc +2 more sources
Post-stroke depression and lesion location: a systematic review [PDF]
, 2015 Post-stroke depression (PSD) is a frequent problem in stroke rehabilitation. Several studies have evaluated association between the lesion location and the risk of depression. Different conclusions and contradictory findings have been published.
Yong, Wu +7 more
core +1 more source
Trunk Control and Lesion Locations According to Alberta Stroke Program Early CT Score in Acute Stroke: A Cross-Sectional Study [PDF]
, 2014 Background: Stroke is a leading cause of disability in elderly people. Lesion location and size, and trunk control early after stroke have been found predictive of functional outcome. Trunk control is an important aspect of postural control, and commonly
Gjelsvik, Bente Elisabeth Bassøe +6 more
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Brain Sciences, 2023 (1) Introduction: Symptom spectrum can be of great diversity and heterogeneity in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) patients in clinical practice.
Youjie Wang, Enhui Zhang, Chen Ye, Bo Wu
doaj +1 more source
Antiepileptics and NO-precursors may be beneficial for stroke-like episodes
eNeurologicalSci, 2019 Pathogenesis and management of stroke-like episodes in mitochondrial disorders is under debate and no consensus has been reached thus far how this phenomenon should be managed. Frequently applied are nitric oxide (NO) precursors but a well-designed study
Josef Finsterer
doaj +1 more source
Data_Sheet_1_Migraine aura-like symptoms at onset of stroke and stroke-like symptoms in migraine with aura.pdf [PDF]
, 2022 Background and objectivesIn general, suddenly occurring neurological deficits, i.e., negative neurological symptoms, are considered symptoms of focal cerebral ischemia, while positive irritative symptoms with gradual onset are viewed as the ...
Arnold, Marcel +28 more
core +2 more sources
Cerebral small vessel disease and stroke: linked by stroke aetiology, but not stroke lesion location or size. [PDF]
BACKGROUND Cerebral small vessel disease (SVD) has previously been associated with worse stroke outcome, vascular dementia, and specific cognitive deficits. The underlying causal mechanisms of these associations are not yet fully understood.
Hakim, Arsany +4 more
core +3 more sources