Results 121 to 130 of about 2,205,053 (308)

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Improving safety and timeliness around nasogastric tube feeding on an Acute stroke unit

BMJ Open Quality
Background/aims Nasogastric tube (NGT) feeding is required for artificial nutrition and hydration in those with impaired swallow due to a stroke. A baseline analysis of new NGT insertions on our acute stroke unit revealed considerable delays in the ...
Manju Krishnan, Tal Anjum, Peter Michael Edward Slade, Sarah Yeap, Bessy Howell, Mary Voulgaridou, Holly Robinson, Hannah Breeze-Jones   +7 more
doaj   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

A study of factors delaying hospital arrival and predictors of mortality in patients presenting to emergency department with Stroke: A developing state scenario [PDF]

, 2010
Background: Thrombolytic therapy for acute ischemic stroke has recently become available in India but its success depends on initiating the treatment in the narrow therapeutic time window.
Khan, Mudassir Azeez, Nagaraja, Vinayak, Sankapithilu, Ganraj Bhat   +2 more
core   +3 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Multidisciplinary experts consensus for assessment and management of vestibular migraine

Chinese Medical Journal, 2019
Stroke and Vertigo Association of Chinese Stroke Association, Xin Chen   +1 more
doaj   +1 more source

Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry

BMJ Open
Purpose Large-scale stroke registries can provide critical insights into disease mechanisms, progression and healthcare needs, informing prevention and care.
David J Werring, Gareth Ambler, Robert Simister, Richard Perry, Parashkev Nachev, Simone Browning, Edgar Chan, Hans R Jäger, Philip S Nash, Raafiah Mussa, Hatice Ozkan, Alex Leff   +11 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Anti-Xa Activity Monitoring for Optimizing Rivaroxaban Dosage in Chinese Patients with Cerebral Venous Thrombosis

Clinical and Applied Thrombosis/Hemostasis
Background Rivaroxaban, a direct Factor Xa inhibitor, is commonly used for cerebral venous thrombosis (CVT) correction. However, pharmacokinetic differences in Chinese may vary in sensitivity and tolerance, resulting in either insufficient or excessive ...
Xiaoming Zhang MD, Meini Gao MD, Duo Lan MD&PhD, Zhongao Wang MD&PhD, Kun Fang MBBS, Xiangyu Ren MBBS, Naiqi Liu MBBS, Da Zhou MD&PhD, Xunming Ji MD&PhD, Ran Meng MD&PhD   +9 more
doaj   +1 more source

Consensus of Experts on the Application of Cardiac Magnetic Resonance in Patients with Ischemic Stroke

Zhongguo cuzhong zazhi
: Stroke is the leading cause of death and disability in Chinese residents, with ischemic stroke (IS) accounting for approximately 70% of stroke patients.
Medical Imaging Society of Chinese Stroke Association; Society of Magnetic Resonance, Chinese Research Hospital Association; Yunnan Stroke Association
doaj   +1 more source