Results 71 to 80 of about 2,146,909 (263)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial:a randomised, double-blind, parallel, placebo-controlled trial [PDF]

, 2010
Epidemiological studies suggest that raised plasma concentrations of total homocysteine might be a risk factor for major vascular events. Whether lowering total homocysteine with B vitamins prevents major vascular events in patients with previous stroke ...
Hankey, G.J., Jamrozik, K., Klijn, C.J., van Bockxmeer, F. M., Hill, M., Gelavis, A., Ferro, J., Lisheng, L., Wong, L., Uddin, W., Eikelboom, J. W., Tan, K., Divjak, I., Baker, R.I., de Freitas, G., Wong, M. C., Eikelboom, J.W., Navarro, J., Slivka, A., Tsiskaridze, A., Lees, K. R., Algra, A., Yi, Q., Ricci, S., Chen, C., Dennis, Martin, Hankey, G. J., Baker, R. I., ?, ?, Groppa, S., Hickling, S. C., Cheung, R., Gommans, J., Spence, J. D., Schmidt, R., Ranawaka, U., Vasikaran, S., et al.   +37 more
core   +1 more source

Progression of Arterial Stiffness is Associated With Midlife Diastolic Blood Pressure and Transition to Late‐Life Hypertensive Phenotypes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Hypertension‐associated cardiovascular events are particularly associated with elevated systolic blood pressure (SBP) in late life, yet long‐term interactions between SBP, diastolic BP (DBP) and arterial stiffness in development of late‐life ...
Alastair John Stewart Webb
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome diagnostic reporting in the 2021–2023 National Health Interview Survey

BMC Public Health
Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic disabling illness characterized by activity limitations associated with fatigue, post-exertional malaise (PEM), unrefreshing sleep, memory and concentration problems ...
Katherine Fleig, Richard Nahin, Barbara Stussman, Miciah Wilkerson, Elizabeth R. Unger, Jin-Mann S. Lin, Brian Walitt   +6 more
doaj   +1 more source

Severity of Intracranial Arterial Calcification on Computed Tomography and Risk of Dementia in Patients With Stroke or Transient Ischemic Attack: A Population‐Based Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Coronary arterial calcification predicts coronary events, but although intracranial arterial calcification on CT (CT‐IAC) is a frequent finding in older individuals, few longitudinal studies have assessed whether its severity or site predict ...
Ke Li (李可), Davide Simonato, Peter M. Rothwell   +2 more
doaj   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Potential of earlier primary care health checks for prevention of cardiovascular events in younger age groups: population-based study in the United Kingdom

BMC Medicine
Background Incidence of stroke and certain cancers is increasing at younger ages in many high-income countries, prompting healthcare systems to consider how best to improve prevention, such as earlier primary care health checks.
Catherine A. Scott, Linxin Li, Peter M. Rothwell   +2 more
doaj   +1 more source

Using routinely acquired electronic patients records (EPRs) and brain imaging to study novel risk factors for vascular dementia in older hospital patients

Cerebral Circulation - Cognition and Behavior
Introduction: Delirium and infection are risk factors for dementia, with infection more strongly linked to vascular than Alzheimer's-type dementia. It is unclear whether regional atrophy and white matter changes (WMC) of vascular origin modify these ...
Emma Colbourne, Emily Boucher, Taylor Hanayik, Katerina Wartolowska, Sarah T Pendlebury   +4 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source