Results 41 to 50 of about 779,727 (355)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Arquivos Brasileiros de Cardiologia, 2008 FUNDAMENTO: Em países desenvolvidos, a insuficiência cardíaca com fração de ejeção preservada (ICFEP) é o modelo mais prevalente que a insuficiência cardíaca com disfunção sistólica (ICDS) na comunidade.
Marco Aurélio Esposito Moutinho +9 more
doaj +1 more source
Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke [PDF]
, 2009 <p><b>Background and Purpose:</b> Clinical research into the treatment of acute stroke is complicated, is costly, and has often been unsuccessful.
Ali, M. +5 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Sensors, 2018 Cardiac stroke volume (SV) is an essential hemodynamic indicator that can be used to assess whether the pump function of the heart is normal. Non-invasive SV measurement is currently performed using the impedance cardiography (ICG).
Shing-Hong Liu +3 more
doaj +1 more source
Stroke volume variation and indexed stroke volume measured using bioreactance predict fluid responsiveness in postoperative children [PDF]
British Journal of Anaesthesia, 2015 Postoperative fluid management can be challenging in children after haemorrhagic surgery. The goal of this study was to assess the ability of dynamic cardiovascular variables measured using bioreactance (NICOM®, Cheetah Medical, Tel Aviv, Israel) to predict fluid responsiveness in postoperative children.Children sedated and mechanically ventilated, who
Vergnaud, E. +6 more
openaire +3 more sources
Heat Transfer Model of Hyporthermic Intracarotid Infusion of Cold Saline for Stroke Therapy [PDF]
, 2006 A 3-dimensional hemispheric computational brain model is developed to simulate infusion of cold saline in the carotid arteries in terms of brain cooling for stroke therapy. The model is based on the Pennes bioheat equation, with four tissue layers: white
Konstas, Angelos-Aristeidis +3 more
core +2 more sources
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Characteristics of High‐Performance Low‐Volume Hospitals in Acute Stroke Care
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground High patient volumes are associated with better stroke management and outcomes. However, in sparsely populated regions, patients with stroke frequently rely on low‐volume hospitals for acute care.
Han‐Yeong Jeong +18 more
doaj +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source