Results 31 to 40 of about 10,735,605 (346)
eLife, 2019 The challenges facing a new independent group leader, principal investigator (PI) or university lecturer are formidable: secure funding, recruit staff and students, establish a research programme, give lectures, and carry out various administrative ...
Sophie E Acton +3 more
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Mesenchymal stromal cells [PDF]
Current Opinion in Hematology, 2006 Our understanding of the biology and properties of mesenchymal stem cells or multipotent mesenchymal stromal cells has expanded dramatically over the last 3 years and is likely to have an impact on clinical practice in the near future, making a review of this topic both timely and relevantRecommendations regarding nomenclature and the definition of ...
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Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
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Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival
Frontiers in Molecular Biosciences, 2022 Regenerative medicine aims to repair degenerate tissue through cell refurbishment with minimally invasive procedures. Adipose tissue (FAT)-derived stem or stromal cells are a convenient autologous choice for many regenerative cell therapy approaches. The
Leon Lufkin +11 more
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Non-Epithelial Thymic Stromal Cells: Unsung Heroes in Thymus Organogenesis and T Cell Development
Frontiers in Immunology, 2021 The stromal microenvironment in the thymus is essential for generating a functional T cell repertoire. Thymic epithelial cells (TECs) are numerically and phenotypically one of the most prominent stromal cell types in the thymus, and have been recognized ...
Takeshi Nitta, Hiroshi Takayanagi
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Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
Stem cell research & therapeutics, 2019 Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based therapy of immune-mediated, inflammatory, and degenerative diseases, due to their immunosuppressive, immunomodulatory, and regenerative potentials.
Nádia de Cássia Noronha NC +7 more
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Cyclin G1 inhibits the proliferation of mouse endometrial stromal cell in decidualization [PDF]
Archives of Biological Sciences, 2017 Uterine stromal cell decidualization is a dynamic physiological process in which cell proliferation, differentiation and apoptosis are orchestrated and occur in a temporal and cell-specific manner. This process is important for successful embryo
Xu Qian +7 more
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Frontiers in Oncology, 2021 Invasion and metastasis are the main reasons for the high mortality of liver cancer, which involve the interaction of tumor stromal cells and malignant cells.
Wentao Jia +3 more
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Are mesenchymal stromal cells immune cells? [PDF]
Arthritis Research & Therapy, 2015 AbstractMesenchymal stromal cells (MSCs) are considered to be promising agents for the treatment of immunological disease. Although originally identified as precursor cells for mesenchymal lineages, in vitro studies have demonstrated that MSCs possess diverse immune regulatory capacities.
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Frontiers in Bioengineering and Biotechnology, 2020 Mesenchymal stromal cell senescence and apoptosis have been identified as critical molecular hallmarks in aging. In this study, we used stromal cell sheet culture as an in vitro model to study the progressive changes of cellular senescence, apoptosis and
Ying Xu +6 more
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