Results 51 to 60 of about 11,256,402 (404)
Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]
, 2013 Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di +7 more
core +1 more source
Cell Reports, 2021 Summary: Hematopoietic stem and progenitor cell (HSPC) engraftment after transplantation during anticancer treatment depends on support from the recipient bone marrow (BM) microenvironment.
Marion Mesnieres +15 more
doaj +1 more source
Adipose-Derived Stromal/Stem Cells [PDF]
Cells, 2020 Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs) [...]
openaire +5 more sources
Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro [PDF]
Stem Cells and Development, 2020 The objective of this study was to determine whether corneal stromal cells (CSCs) from the limbal and central corneal stroma in dogs have multipotent mesenchymal stem/stromal cell (MSC) properties, and whether this cell population can be differentiated into keratocyte-like cells (KDCs). Normal, donated, mesocephalic dog corneas were used to isolate CSC
Kafarnik, C +4 more
openaire +3 more sources
Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
semanticscholar +1 more source
Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity
Cell ReportsSummary: Lymph nodes are uniquely organized niches for immune interactions. Fibroblastic reticular cells (FRCs) facilitate immune cell communication and regulate immune function by producing growth factors, chemokines, and inflammatory cues.
Spyridon Makris +12 more
doaj +1 more source
B Cell–Activating Factor Promotes B Cell Survival in Ectopic Lymphoid Tissues in Nasal Polyps
Frontiers in Immunology, 2021 Ectopic lymphoid tissues (eLTs) characterized by B cell aggregation contribute to the local immunoglobulin production in nasal polyps (NPs). B cell-activating factor (BAFF) is vital for B cell survival, proliferation, and maturation.
Zhe-Zheng Wang +7 more
doaj +1 more source
Mechanisms of mesenchymal stem/stromal cell function
Stem cell research & therapeutics, 2016 The past decade has seen an explosion of research directed toward better understanding of the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair of injured organs and tissues.
Jeffrey L Spees, R. Lee, C. Gregory
semanticscholar +1 more source
Interplay between Solid Tumors and Tumor Microenvironment
Frontiers in Immunology, 2022 Over the past few decades, basic studies aimed at curing patients with cancer have been constantly evolving. A myriad of mechanistic studies on physiological changes and related factors in tumor growth and metastasis have been reported. Recently, several
Seung-Jin Kim +4 more
doaj +1 more source
Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]
, 2017 Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F. +4 more
core +1 more source