Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
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Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity. [PDF]
, 2012 Although chemotherapy is used to treat most advanced solid tumors, recurrent disease is still the major cause of cancer-related mortality. Cancer stem cells (CSCs) have been the focus of intense research in recent years because they provide a possible ...
de la Cruz, Cecile +5 more
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Journal of Medical Case Reports, 2023 Background During neoadjuvant chemotherapy for giant gastrointestinal stromal tumors, changes in gastrointestinal stromal tumor size are rarely associated with events such as perforation and bleeding that require emergency surgery.
Yoichi Sugiyama +5 more
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Gastrointestinal stromal tumor metastasis to the ovary: A case report
SAGE Open Medical Case Reports, 2021 Gastrointestinal stromal tumors are common mesenchymal tumors of the gastrointestinal tract. The major site of metastasis for gastrointestinal stromal tumors is the liver or peritoneum, while metastasis to the ovary is exceptionally rare.
Takahisa Yamaguchi +12 more
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Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces [PDF]
, 2015 The diverse composition and structure of extracellular matrix (ECM) interfaces encountered by tumor cells at secondary tissue sites can influence metastatic progression. Extensive in vitro and in vivo data has confirmed that metastasizing tumor cells can
Caley, Matthew P. +7 more
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Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
, 2020 Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
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Duodenal Gastrointestinal Stromal Tumor
Journal of Clinical and Biomedical Sciences, 2019 Gastrointestinal stromal tumors (GIST) are nonepithelial tumors arising from the interstitial cells of Cajal. They express KIT protein-CD117 on immunohistochemistry.
Divya Teja Patil +3 more
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Rare Ovary Sclerosis Stromal Tumor: Case Report [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020 Introduction: Sclerosing stromal tumor (SST) is a rare tumor of sex cord stromal tumor. Regarding to specific clinical, historical and hormonal feature, it has been differentiated from sex cord stromal tumor.
Setareh Akhavan +5 more
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Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies
Frontiers in Cell and Developmental Biology, 2023 Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano +10 more
doaj +1 more source
Chronic Disseminated Intravascular Coagulation in Patient With Metastatic Gastrointestinal Stromal Tumor: Treating Bleeding With Anticoagulation. [PDF]
J Med CasesBopp E, Cui Z, Elkon J.
europepmc +3 more sources