Results 81 to 90 of about 4,026,358 (295)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

On the Strong Approximation of Pure Jump Processes [PDF]

This paper constructs strong discrete time approximations for pure jump processes that can be described by stochastic differential equations. Strong approximations based on jump-adapted time discretizations, which produce no discretization bias, are ...
Nicola Bruti-Liberati, Eckhard Platen
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Strong Convergence Theorems for Lipschitzian Demicontraction Semigroups in Banach Spaces

Fixed Point Theory and Applications, 2011
The purpose of this paper is to introduce and study the strong convergence problem of the explicit iteration process for a Lipschitzian and demicontraction semigroups in arbitrary Banach spaces.
Cho YeolJe, Lee HWJoseph, Chan ChiKin, Chang Shih-sen   +3 more
doaj   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Strong almost convergence with respect to an Orlicz function

Miskolc Mathematical Notes
In this paper, using an Orlicz function we extend the concept of strong almost convergence and show that strong almost convergence, uniform statistical convergence and strong almost convergence with respect to an Orlicz function are all equivalent on ...
İlknur Özgüç
doaj   +1 more source

Strong convergence rate of truncated Euler-Maruyama method for stochastic differential delay equations with Poisson jumps. [PDF]

Front Math China, 2021
Gao S, Hu J, Tan L, Yuan C.
europepmc   +1 more source

Price Convergence in the EU Poultry and Eggs Markets [PDF]

This paper uses the notions of convergence in ratio and of convergence in difference to investigate price convergence for poultry and eggs in geographically separated EU markets.
Panos Fousekis
core  

Strong convergence for large bodies in micromagnetics

, 2007
The convexified Landau-Lifshitz minimisation problem in micromagnetics leads to a degenerate variational problem. Therefore strong convergence of finite element approximations cannot be expected in general.
Wolfgang Boiger, Carstensen, Carsten, Praetorius, Dirk, Boiger, Wolfgang, Carsten Carstensen, Dirk Praetorius   +5 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source