Results 81 to 90 of about 105,298 (255)

Responses of Macroinvertebrate Communities to Heterogeneity Among Typical Reaches in the Upper Yangtze River

open access: yesEcology and Evolution
Benthic macroinvertebrates are important indicators of river ecosystem health, and their spatial distribution is highly sensitive to environmental heterogeneity. In large mountainous rivers characterized by complex geomorphology and strong hydrodynamics,
Yang Wei   +9 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Formal software measurements for object-oriented business models. [PDF]

open access: yes
This paper presents a set of metrics and pseudo-metrics for the measurement of conceptual distances in M.E.R.O.D.E. business models. The measures are developed and validated using measure and measurement theory.
Dedene, Guido, Poels, Geert
core  

Proposed industry funding model for the Australian Securities and Investments Commission [PDF]

open access: yes, 2015
On 7 December 2014, the Government released the Final Report of the Financial System Inquiry, an inquiry which sets out a \u27blueprint\u27 for Australia\u27s financial system over the coming decades.
Department of the Treasury (Australia)
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

On the (k, t)-metric dimension of a graph [PDF]

open access: yes, 2016
En aquesta tesi s'estudia la dimensió (k,t)-mètrica dels grafs. Particularment s'emfatitza en la dimensió k-mètrica i la dimensió de k-adjacència. Al primer capítol es dedica als conceptes bàsics i les notacions emprades a la tesi.
Estrada Moreno, Alejandro
core  

Chaos to Multiple Mappings [PDF]

open access: yes, 2017
Let [Formula: see text] be a compact metric space and [Formula: see text] be an [Formula: see text]-tuple of continuous selfmaps on [Formula: see text].
Yingcui Zhao   +3 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Unsupervised statistical learning underpins computational, behavioural, and neural manifestations of musical expectation [PDF]

open access: yes, 2010
The ability to anticipate forthcoming events has clear evolutionary advantages, and predictive successes or failures often entail significant psychological and physiological consequences.
Pearce, Marcus T.   +4 more
core   +1 more source

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