Results 61 to 70 of about 48,502 (244)

Near horizon structure of extremal vanishing horizon black holes

Nuclear Physics B, 2015
We study the near horizon structure of Extremal Vanishing Horizon (EVH) black holes, extremal black holes with vanishing horizon area with a vanishing one-cycle on the horizon.
S. Sadeghian, M.M. Sheikh-Jabbari, M.H. Vahidinia, H. Yavartanoo   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

On Distance and Strong Metric Dimension of the Modular Product

Bulletin of the Malaysian Mathematical Sciences Society
The modular product $G\diamond H$ of graphs $G$ and $H$ is a graph on vertex set $V(G)\times V(H)$. Two vertices $(g,h)$ and $(g',h')$ of $G\diamond H$ are adjacent if $g=g'$ and $hh'\in E(H)$, or $gg'\in E(G)$ and $h=h'$, or $gg'\in E(G)$ and $hh'\in E(H)$, or (for $g\neq g'$ and $h\neq h'$) $gg'\notin E(G)$ and $hh'\notin E(H)$.
Cong X. Kang, Aleksander Kelenc, Iztok Peterin, Eunjeong Yi   +3 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Disordered Heterogeneous Universe: Galaxy Distribution and Clustering across Length Scales

Physical Review X, 2023
The studies of disordered heterogeneous media and galaxy cosmology share a common goal: analyzing the disordered distribution of particles and/or building blocks at microscales to predict physical properties of the medium at macroscales, whether it be a ...
Oliver H. E. Philcox, Salvatore Torquato   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Strong metric dimensions of unicyclic graphs

Mohyla Mathematical Journal, 2018
Вершина w простого зв’язного графа G сильно роздiляє двi вершини u i v цього графа, якщо виконується одна з двох рiвностей: dG(w, u) = dG(w, v) + dG(v, u) або dG(w, v) = dG(w, u) + dG(u, v). Множина S найменшої потужностi, елементи якої сильно роздiляють довiльну пару вершин графа G, називається сильним метричним базисом графа G.
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source