Results 61 to 70 of about 544,762 (274)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
On strong geodeticity in the lexicographic product of graphs
AIMS MathematicsThe strong geodetic number of a graph and its edge counterpart are recent variations of the pioneering geodetic number problem. Covering every vertex and edge of $ G $, respectively, using a minimum number of vertices and the geodesics connecting them ...
S. Gajavalli, A. Berin Greeni
doaj +1 more source
Bootstrap Percolation in Strong Products of Graphs
The Electronic Journal of CombinatoricsGiven a graph $G$ and assuming that some vertices of $G$ are infected, the $r$-neighbor bootstrap percolation rule makes an uninfected vertex $v$ infected if $v$ has at least $r$ infected neighbors. The $r$-percolation number, $m(G,r)$, of $G$ is the minimum cardinality of a set of initially infected vertices in $G$ such that after continuously ...
Brešar, Boštjan, Hedžet, Jaka
openaire +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Observations on the Lovász θ-Function, Graph Capacity, Eigenvalues, and Strong Products
Entropy, 2023 This paper provides new observations on the Lovász θ-function of graphs. These include a simple closed-form expression of that function for all strongly regular graphs, together with upper and lower bounds on that function for all regular graphs.
Igal Sason
doaj +1 more source
, 2014 The bondage number $b(G)$ of a nonempty graph $G$ is the cardinality of a smallest set of edges whose removal from $G$ results in a graph with domination number greater than the domination number of $G$. Here we study the bondage number of some grid-like
Bauer +18 more
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
On eternal domination and Vizing-type inequalities
AKCE International Journal of Graphs and Combinatorics, 2020 We show sharp Vizing-type inequalities for eternal domination. Namely, we prove that for any graphs G and H, where is the eternal domination function, α is the independence number, and is the strong product of graphs.
Keith Driscoll +4 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source