Results 71 to 80 of about 549,593 (301)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
On eternal domination and Vizing-type inequalities
AKCE International Journal of Graphs and Combinatorics, 2020 We show sharp Vizing-type inequalities for eternal domination. Namely, we prove that for any graphs G and H, where is the eternal domination function, α is the independence number, and is the strong product of graphs.
Keith Driscoll +4 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Interval-Valued Fuzzy Soft Graphs
Topological Algebra and its Applications, 2017 In this paper, we combine concepts of interval-valued fuzzy soft sets and graph theory. Then we introduce notations of interval-valued fuzzy soft graphs and complete interval-valued fuzzy soft graphs.
Zihni Onur +2 more
doaj +1 more source
Forgotten Index of Generalized Operations on Graphs
Journal of Chemistry, 2021 In theoretical chemistry, several distance-based, degree-based, and counting polynomial-related topological indices (TIs) are used to investigate the different chemical and structural properties of the molecular graphs. Furtula and Gutman redefined the F-
Muhammad Javaid +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
An Isomorphism Theorem for Graphs [PDF]
, 2009 In the 1970’s, L. Lovász proved that two graphs G and H are isomorphic if and only if for every graph X , the number of homomorphisms from X → G equals the number of homomorphisms from X → H .
Culp, Laura
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Estimates for the Norm of Generalized Maximal Operator on Strong Product of Graphs [PDF]
, 2021 Zaryab Hussain +3 more
openalex +1 more source