Results 141 to 150 of about 10,261,192 (285)
Strong Convergence Properties and Strong Stability for Weighted Sums of AANA Random Variables
Zhiyong Chen +3 more
doaj +1 more source
On strong stability of linear Poisson actions
Linear Poisson actions of the group Rm are considered. Conditions on the joint spectrum of the generators and on the centralizers assuring stability and strong stability of the action are given. We give also some examples of Poisson actions usingCAS ”Mathematica”.
Glavan, V., Rzeszotko, Z.
openaire +2 more sources
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
On Decentrally Simultaneous Stabilization and Strong Stabilization
Hongye DU +2 more
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Strong stability of 3-wise t-intersecting families
Let ${\mathcal G}$ be a family of subsets of an $n$-element set. The family ${\mathcal G}$ is called $3$-wise $t$-intersecting if the intersection of any three subsets in ${\mathcal G}$ is of size at least $t$. For a real number $p\in(0,1)$ we define the measure of the family by the sum of $p^{|G|}(1-p)^{n-|G|}$ over all $G\in{\mathcal G}$. For example,
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

