Results 41 to 50 of about 95,473 (252)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Increasing performance and stability of mass-manufacturable biobatteries by ink modification
Sensing and Bio-Sensing Research, 2015 In this work, biobatteries assembled using roll-to-roll screen printed enzymatic electrodes were characterised in terms of their electrical performance and storage stability.
Saara Tuurala +3 more
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Step Sizes for Strong Stability Preservation with Downwind-Biased Operators [PDF]
SIAM Journal on Numerical Analysis, 2011 Strong stability preserving (SSP) integrators for initial value ODEs preserve temporal monotonicity solution properties in arbitrary norms. All existing SSP methods, including implicit methods, either require small step sizes or achieve only first order accuracy.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Transformed implicit-explicit DIMSIMs with strong stability preserving explicit part [PDF]
Numerical Algorithms, 2019 For many systems of differential equations modeling problems in science and engineering, there are often natural splittings of the right hand side into two parts, one of which is non-stiff or mildly stiff, and the other part is stiff. Such systems can be efficiently treated by a class of implicit-explicit (IMEX) diagonally implicit multistage ...
Izzo G., Jackiewicz Z.
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Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
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Optimal implicit strong stability preserving Runge–Kutta methods
Applied Numerical Mathematics, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ketcheson, D, Macdonald, C, Gottlieb, S
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