Results 81 to 90 of about 430,778 (289)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
AIP Advances, 2015 In this paper, a modified cubic B-spline differential quadrature method (MCB-DQM) is employed for the numerical simulation of two-space dimensional nonlinear sine-Gordon equation with appropriate initial and boundary conditions.
H. S. Shukla +2 more
doaj +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Journal of Inequalities and ApplicationsIn this paper, we introduce a new four-step iterative process for approximating fixed points of generalized α-nonexpansive multivalued mappings in uniformly convex Banach spaces.
Makbule Kaplan Özekes
doaj +1 more source
, 2009 We study stability conditions induced by functors between triangulated categories. Given a finite group acting on a smooth projective variety we prove that the subset of invariant stability conditions embeds as a closed submanifold into the stability ...
Macri, Emanuele +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Implicit-explicit methods based on strong stability preserving multistep time discretizations [PDF]
, 2003 Thor Gjesdal
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OrganogenesisDecellularized blood vessels with low immunogenicity and excellent biocompatibility are promising for tissue engineering and clinical applications.
Hongguang Chen +6 more
doaj +1 more source
Downwinding for Preserving Strong Stability in Explicit Integrating\n Factor Runge--Kutta Methods [PDF]
, 2018 Leah Isherwood +2 more
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source