Results 121 to 130 of about 2,919,635 (295)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Almost Strongly Regular Graphs [PDF]
We investigate what we call (δ, )-almost strongly regular graphs with parameters (n,k,λ,µ). In particular, we generalize some well known results and bounds on the parameters of strongly regular graphs from Bose and Dowling (1963) and Babai (1980, 2014 ...
Gomez, Josias
core
Coefficients Of The Inverse Of Strongly Starlike Functions. [PDF]
, 2003 For the class of strongly starlike functions, sharp bounds on the first four coefficients of the inverse functions are determined. A sharp estimate for the Fekete-Szego coefficient functional is also obtained.
M. Ali, Roslhan
core +1 more source
On the Nomura algebras of formally self-dual association schemes of class 2 [PDF]
Transactions on Combinatorics, 2013 In this paper, the type-II matrices on (negative) Latin square graphs are considered and it is proved that, under certain conditions, the Nomura algebras of such type-II matrices are trivial.
Amir Rahnamai Barghi, Azam Hosseini
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
, 2022 Strongly regular graphs are certain very regular structures found in statistical design, finite group theory, coding theory and quantum information theory. This monograph gives a detailed survey of theory and examples.
Van Maldeghem, Hendrik +1 more
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source