Results 101 to 110 of about 2,975,002 (298)

Fault-tolerant quantum speedup from constant depth quantum circuits

open access: yesPhysical Review Research, 2020
A defining feature in the field of quantum computing is the potential of a quantum device to outperform its classical counterpart for a specific computational task.
Rawad Mezher   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Co-cliques and star complements in extremal strongly regular graphs [PDF]

open access: yes, 2006
Suppose that the positive integer μ is the eigenvalue of largest multiplicity in an extremal strongly regular graph G. By interlacing, the independence number of G is at most 4μ2 + 4μ - 2.
Rowlinson, Peter   +2 more
core   +1 more source

Self-Dual and LCD Codes from Kneser Graphs K(n, 2) and Generalized Quadrangles

open access: yesMathematics
In this paper, we study self-dual and LCD codes constructed from Kneser graphs K(n, 2) and collinearity graphs of generalized quadrangles using the so-called pure and bordered construction. We determine conditions under which these codes are self-dual or
Dean Crnković, Ana Grbac
doaj   +1 more source

Detection of Network Motif Based on a Novel Graph Canonization Algorithm from Transcriptional Regulation Networks

open access: yesMolecules, 2017
Network motifs are patterns of complex networks occurring significantly more frequently than those in random networks. They have been considered as fundamental building blocks of complex networks.
Jialu Hu, Xuequn Shang
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

On Almost Distance-Regular Graphs [PDF]

open access: yes
2010 Mathematics Subject Classification: 05E30, 05C50;distance-regular graph;walk-regular graph;eigenvalues;predistance ...
Fiol, M.A.   +4 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

On valency of Strongly regular graph with p^2 vertices [PDF]

open access: yes, 1998
P(論文)"A graph Γ is called strongly regular, if each vertex is adjacent to κ vertices, each adjacent pair of vertices has λ between vertices, each non-adjacent pair of vertices has μ between vertices.
IWANE, Hiroshi   +5 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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