Results 101 to 110 of about 3,100,536 (300)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Non-existence of quasi-symmetric designs having certain pseudo-geometric block graphs

AKCE International Journal of Graphs and Combinatorics
The block graph of a quasi-symmetric design is strongly regular. It is a challenging problem to decide which strongly regular graphs are block graphs of quasi-symmetric designs.
Kusum S. Rajbhar, Rajendra M. Pawale
doaj   +1 more source

Strongly Regular Fusions of Tensor Products of Strongly Regular Graphs

Rocky Mountain Journal of Mathematics, 1994
Let \(G\) and \(H\) be strongly regular graphs with (0, 1)-adjacency matrices \(A_ 0= I\), \(A_ 1\), \(A_ 2= J-I- A_ 1\) and \(B_ 0= I\), \(B_ 1,\) \(B_ 2= J- I- B_ 1\) respectively. The tensor product \(G\otimes H\) is defined to be the nine class association scheme with adjacency matrices \(A_ i\otimes B_ j\). By combining (fusing) some of these nine
openaire   +2 more sources

Some Implications on Amorphic Association Schemes [PDF]

AMS classifications: 05E30, 05B20;amorphic association scheme;strongly regular graph;(negative) Latin square type;cyclotomic association scheme;strongly regular ...
Dam, E.R. van, Muzychuk, M.
core  

On automorphisms of a strongly regular graph with parameters (210,95,40,45)

, 2012
Possible orders of automorphisms of a strongly regular graph with parameters (210,95,40,45) and the structure of fixed-point subgraphs of these automorphisms are found.
Chuksina, N. V., Makhnev, A. A.
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Universal Adjacency Matrices with Two Eigenvalues [PDF]

AMS Mathematics Subject Classification: 05C50.Adjacency matrix;Universal adjacency matrix;Laplacian matrix;signless Laplacian;Graph spectra;Eigenvalues;Strongly regular ...
Omidi, G.R., Haemers, W.H.
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

On Almost Distance-Regular Graphs [PDF]

2010 Mathematics Subject Classification: 05E30, 05C50;distance-regular graph;walk-regular graph;eigenvalues;predistance ...
Fiol, M.A., Dalfo, C., Gorissen, B.L., Garriga, E., Dam, E.R. van   +4 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source