Results 81 to 90 of about 3,100,536 (300)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On Strongly Regular Graphs and the Friendship Theorem
MathematicsThis paper presents an alternative proof of the celebrated friendship theorem, originally established by Erdős, Rényi, and Sós in 1966. The proof relies on a closed-form expression for the Lovász ϑ-function of strongly regular graphs, recently derived by
Igal Sason
doaj +1 more source
International Journal of Mathematics and Mathematical Sciences, 1985 In this paper we define a topological space X to be θ-regular if every filterbase in X with a nonempty θ-adherence has a nonempty adherence. It is shown that the class of θ-regular topological spaces includes rim-compact topological spaces and that θ ...
Dragan S. Janković
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On the locating matrix of a graph and its spectral analysis [PDF]
Computer Science Journal of Moldova, 2017 We introduce a new matrix representation for a graph by defining the locating matrix $\mathbf{Lo}(G)$ of $G$. We define the locating eigenvalues, the locating spectrum, and locating energy of the graph and we calculate them for some standard graphs.
H. N. Ramaswamy +2 more
doaj
On outindependent subgraphs of strongly regular graphs [PDF]
, 2006 An outindependent subgraph of a graph G, with respect to an independent vertex subset C¿¿V, is the subgraph GC induced by the vertices in V\¿C. We study the case when G is strongly regular, where the results of de Caen [1998, The spectra of complementary
Garriga Valle, Ernest +1 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Rotation-based schedules in elementary schools to prevent COVID-19 spread: a simulation study
Scientific Reports, 2023 Rotations of schoolchildren were considered as a non-pharmacological intervention in the COVID-19 pandemic. This study investigates the impact of different rotation and testing schedules.We built an agent-based model of interactions among pupils and ...
Cyril Brom +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source