Results 71 to 80 of about 370,627 (270)
The asymptotics of strongly regular graphs [PDF]
A strongly regular graph is called trivial if it or its complement is a union of disjoint cliques. We prove that every infinite family of nontrivial strongly regular graphs is quasi-random in the sense of Chung, Graham and ...
Nikiforov, Vladimir
core
New bounds for the max-$k$-cut and chromatic number of a graph
We consider several semidefinite programming relaxations for the max-$k$-cut problem, with increasing complexity. The optimal solution of the weakest presented semidefinite programming relaxation has a closed form expression that includes the largest ...
Sotirov, Renata, van Dam, Edwin R.
core +2 more sources
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Cayley graph built upon the semigroup of left ideals of a ring
We investigate the interaction between a ring R and the Cayley graph Cay(L(R)) of the semigroup of left ideals of R,as well as subdigraphs of this graph.Graph theoretic properties of these graphs are investigated,such as transitive closure,girth,radius ...
Aihua Li, Ralph P.Tucci
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
rc-continuous functions and functions with rc-strongly closed graph
The family of regular closed subsets of a topological space is used to introduce two concepts concerning a function f from a space X to a space Y. The first of them is the notion of f being rc-continuous.
Bassam Al-Nashef
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Strongly Regular Graphs with Parameters (4m4, 2m4 + m2, m4 + m2, m4 + m2) Exist for All m>1 [PDF]
Using results on Hadamard difference sets, we construct regular graphical Hadamard matrices of negative type of order 4m4 for every positive integer m. If m > 1, such a Hadamard matrix is equivalent to a strongly regular graph with parameters (4m4, 2m4 ...
Haemers, W.H., Xiang, Q.
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source

