Results 61 to 70 of about 491,070 (354)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

GRAPHS \(\Gamma\) OF DIAMETER 4 FOR WHICH \(\Gamma_{3,4}\) IS A STRONGLY REGULAR GRAPH WITH \(\mu=4,6\)

Ural Mathematical Journal
We consider antipodal graphs \(\Gamma\) of diameter 4 for which  \(\Gamma_{1,2}\) is a strongly regular graph. A.A. Makhnev and D.V. Paduchikh noticed that, in this case, \(\Delta=\Gamma_{3,4}\) is a strongly regular graph without triangles.
Alexander A. Makhnev, Mikhail P. Golubyatnikov, Konstantin S. Efimov   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Homomorphisms of strongly regular graphs [PDF]

Algebraic Combinatorics, 2016
We prove that if G and H are primitive strongly regular graphs with the same parameters and φ is a homomorphism from G to H, then φ is either an isomorphism or a coloring (homomorphism to a complete subgraph). Moreover, any such coloring is optimal for G and its image is a maximum clique of H.
openaire   +4 more sources

On highly regular strongly regular graphs [PDF]

Algebraic Combinatorics, 2021
In this paper we unify several existing regularity conditions for graphs, including strong regularity, k-isoregularity, and the t-vertex condition. We develop an algebraic composition/decomposition theory of regularity conditions. Using our theoretical results we show that a family of non rank 3 graphs known to satisfy the 7-vertex condition fulfills ...
openaire   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

On Automorphisms of a Distance-Regular Graph with Intersection Array {125,96,1;1,48,125} [PDF]

Учёные записки Казанского университета: Серия Физико-математические науки, 2017
J. Koolen posed the problem of studying distance-regular graphs in which neighborhoods of vertices are strongly regular graphs with the second eigenvalue ≤ t for the given positive integer t.
V.V. Bitkina, A.A. Makhnev
doaj  

Cyclotomic Trace Codes

Algorithms, 2019
A generalization of Ding’s construction is proposed that employs as a defining set the collection of the sth powers ( s ≥ 2 ) of all nonzero elements in G F ( p m ) , where p ≥ 2 is prime.
Dean Crnković, Andrea Švob, Vladimir D. Tonchev   +2 more
doaj   +1 more source