Results 41 to 50 of about 28,901 (265)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
On the locating matrix of a graph and its spectral analysis [PDF]
Computer Science Journal of Moldova, 2017 We introduce a new matrix representation for a graph by defining the locating matrix $\mathbf{Lo}(G)$ of $G$. We define the locating eigenvalues, the locating spectrum, and locating energy of the graph and we calculate them for some standard graphs.
H. N. Ramaswamy +2 more
doaj
Complete Weight Enumerators of a Class of Linear Codes From Weil Sums
IEEE Access, 2020 By appropriately choosing a defining set, we define a class of linear codes and determine their complete weight enumerators and weight enumerators using Weil sums.
Shudi Yang
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Roughness Evaluation of Burnished Topography with a Precise Definition of the S-L Surface
Applied Sciences, 2022 Studies of surface topography including processes of measurement and data analysis have an influence on the description of machined parts with their tribological performance.
Przemysław Podulka
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Generalized quadrangles and subconstituent algebra ¹
Cubo, 2010 The point graph of a generalized quadrangle GQ (s, t) is a strongly regular graph G = srg( ?, ?, ?, μ) whose parameters depend on s and t. By a detailed analysis of the adjacency matrix we compute the Terwilliger algebra of this kind of graphs (and ...
Fernando Levstein, Carolina Maldonado
doaj
Observations on graph invariants with the Lovász ϑ-function
AIMS MathematicsThis paper delves into three research directions, leveraging the Lovász $ \vartheta $-function of a graph. First, it focuses on the Shannon capacity of graphs, providing new results that determine the capacity for two infinite subclasses of strongly ...
Igal Sason
doaj +1 more source
The lower bound for number of hexagons in strongly regular graphs with parameters $\lambda=1$ and $\mu=2$ [PDF]
E-Journal of Analysis and Applied MathematicsThe existence of $srg(99,14,1,2)$ has been a question of interest for several decades to the moment. In this paper, we consider the structural properties in general for the family of strongly regular graphs with parameters $\lambda =1$ and $\mu =2$.
Reimbay Reimbayev
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source