Results 71 to 80 of about 49,410 (256)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions

open access: yesChemosensors, 2016
Strontium-82 is produced by proton activation of a rubidium chloride target in an accelerator or cyclotron and purified by ion exchange chromatography. The Strontrium-82 is used in Cardigen generators to produce Rubidium-82 for cardiac imaging.
Jonathan Fitzsimmons
doaj   +1 more source

Strontium- and lead-isotope composition of some basalts at DSDP Hole 69-504B

open access: yes, 1983
Seventeen whole-rock samples, generally taken at 25- to 50-meter intervals from 5 to 560 meters sub-basement in Deep Sea Drilling Project Hole 504B, were analyzed for 87Sr/86Sr ratios, and rubidium and strontium concentrations.
T J Barrett (6962990), Barrett, T J
core   +1 more source

The Precambrian marine carbonate isotope database: version 1.1. [PDF]

open access: yes, 2002
We present a compilation of strontium, carbon, and oxygen isotope compositions of roughly 10,000 marine carbonate rocks of Archean - Ordovician age (3800 Ma – 450 Ma).
Shields, GA   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Strontium-Substituted Nanohydroxyapatite-Incorporated Poly(lactic acid) Composites for Orthopedic Applications: Bioactive, Machinable, and High-Strength Properties

open access: yes, 2023
Traditional metal-alloy bone fixation devices provide structural support for bone repair but have limitations in actively promoting bone healing and often require additional surgeries for implant removal.
Jukka V. Seppälä (2176416)   +6 more
core   +2 more sources

Strontium isotope stratigraphy in the Late Cretaceous: Numerical calibration of the Sr isotope curve and intercontinental correlation for the campanian [PDF]

open access: yes, 1993
The white Chalk exposed in quarries at Lagerdorf and Kronsmoor, northwestern Germany, provides a standard section for the European Upper Cretaceous.
Chen, M   +9 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

A normalised seawater strontium isotope curve: possible implications for Neoproterozoic-Cambrian weathering rates and the further oxygenation of the Earth [PDF]

open access: yes, 2007
The strontium isotope composition of seawater is strongly influenced on geological time scales by changes in the rates of continental weathering relative to ocean crust alteration.
Shields, GA, Shields, G. A.
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

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