Results 71 to 80 of about 184,091 (354)

Distribution Characteristics and Formation Mechanism of Strontium-Enriched Groundwater in the Taxiutan of Gonghe Basin, Qinghai Province

open access: yesYankuang ceshi
Qinghai Province possesses abundant high-quality natural mineral water resources, particularly characterized by strontium-enriched mineral waters. However, previous studies have primarily focused on strontium-enriched water bodies in karst regions, with ...
Yi LIU   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The effects of strontium-90 on mice [PDF]

open access: yes, 1959
On Sept. 19, 1958 there was published in Science a paper by Dr. Miriam P. Finkel of Argonne National Laboratory in which she communicated her observations on the effects of strontium-90 injected into mice on life expectancy and on incidence of tumors of ...
Kamb, Barclay, Pauling, Linus
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Strontium isotope (87Sr/86Sr) data from archaeological sites in Utah, USA

open access: yesData in Brief, 2019
The information presented here includes the results of strontium isotope analysis on 75 baseline samples from nine Fremont sites in Utah. The baseline samples are of lagomorphs and rodents with limited foraging ranges.
Spencer F.X. Lambert
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Application of hydrochemistry and strontium isotope for understanding the hydrochemical characteristics and genesis of strontium-rich groundwater in karst area, Gongcheng County, Southwest China

open access: yesJournal of Groundwater Science and Engineering
Understanding the hydrochemical characteristics and genesis mechanisms of strontium-rich groundwater is pivotal for supporting the exploitation and utilization of natural strontium-rich groundwater. In this research, 27 groundwater samples were collected.
Mi Tang   +5 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Chemostratigraphy of Neoproterozoic carbonates: implications for 'blind dating' [PDF]

open access: yes, 2001
The delta C-13(carb) and Sr-87/Sr-86 secular variations in Neoproteozoic seawater have been used for the purpose of 'isotope stratigraphy' but there are a number of problems that can preclude its routine use.
Aharon P.   +55 more
core   +1 more source

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