Results 31 to 40 of about 424,040 (244)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Excited state spatial distributions in a cold strontium gas [PDF]
, 2012 This thesis describes the development of a new technique for measuring the spatial distribution of Rydberg atoms in a cold strontium gas. Strontium atoms are cooled and trapped in a magneto-optical trap and coherently excited to Rydberg states in a two ...
LOCHEAD, GRAHAM
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Collective atomic scattering and motional effects in a dense coherent medium
Nature Communications, 2016 Light scattering from a dense coherent medium is determined by the interplay of dispersive and radiative dipole–dipole interactions. Here, the authors control the motional effects that obscure the coherence of scattered light and study collective ...
S. L. Bromley +11 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Hallmarks of the Mott-metal crossover in the hole-doped pseudospin-1/2 Mott insulator Sr2IrO4
Nature Communications, 2016 The physics of Mott insulators is obscured by the interplay between competing orders and fluctuations. Here, the authors track the evolution of the electronic structure of Mott insulator strontium iridate as the iridium atoms are replaced by rhodium ...
Yue Cao +15 more
doaj +1 more source
Number-resolved imaging of $^{88}$Sr atoms in a long working distance optical tweezer
SciPost Physics, 2020 We demonstrate number-resolved detection of individual strontium atoms in a long working distance low numerical aperture (NA = 0.26) tweezer. Using a camera based on single-photon counting technology, we determine the presence of an atom in the ...
Niamh Christina Jackson, Ryan Keith Hanley, Matthew Hill, Frédéric Leroux, Charles S. Adams, Matthew Philip Austin Jones
doaj +1 more source
Acknowledgment to Reviewers of Atoms in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Atoms maintains its standards for the high quality of its published papers [...
Atoms Editorial Office Atoms Editorial Office
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source