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Automating eligibility assessment and enrollment for sugammadex administration within an integrated perioperative workflow. [PDF]
Gabel E +4 more
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Keeping the Air On: Energy Security and Social Work in European Home Respiratory Therapy. [PDF]
Gómez Pedrajas EM +2 more
europepmc +1 more source
Integration of large vision language models for efficient post-disaster damage assessment and reporting. [PDF]
Chen Z +4 more
europepmc +1 more source
Letter to the editor: A la Recherche de la Normalité Perdue. [PDF]
Pennings, J.M., Wijk, C.G. van
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Structural alerts for estimating the carcinogenicity of pesticides and biocides
SAR and QSAR in Environmental Research, 2011More than 20 years ago, Ashby and Tennant showed the interest of structural alerts for the prediction of the carcinogenicity of chemicals. These structural alerts are functional groups or structural features of various sizes that are linked to the level of carcinogenicity of chemicals.
J Devillers, Enrico Mombelli
exaly +4 more sources
Mutagenic potential and structural alerts of phytotoxins
Food and Chemical Toxicology, 2023Toxic plant-produced chemicals, so-called phytotoxins, constitute a category of natural compounds belonging to a diversity of chemical classes. Some of them (e.g., alkaloids, terpenes, saponins) are associated with high toxic potency, while for many of others no toxicological data is available. In this study, the mutagenic potential of 1586 phytotoxins,
Arianna Bassan +2 more
openaire +2 more sources
From Structural Alerts to Signature Fragment Alerts: A Case Study on Pyrrolizidine Alkaloids
Chemical Research in Toxicology, 2023Even though modeling is considered a valid alternative to mutagenicity testing for substances with known structures, it can be applied for mixtures only if all of the single chemical structures are identified. Within the present work, we investigate a new avenue to exploit computational toxicology for mixtures, such as plant-based food ingredients ...
Elena Lo Piparo +2 more
openaire +2 more sources
Structural alerts for the identification of bioaccumulative compounds
Integrated Environmental Assessment and Management, 2018Abstract Legislators have included bioaccumulation in the evaluation of chemicals in the framework of the European Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation.
Valsecchi, C +3 more
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