Results 241 to 250 of about 82,891 (271)
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Structure, microphysics, and surface area of the Arctic snowpack near Alert during the ALERT 2000 campaign

Atmospheric Environment, 2002
The seasonal snowpackat Alert (North coast of Ellesmere Island, 82 129.94 0 N, 62120.55 0 W) was studied in February and April 2000, on land and on sea ice. The stratigraphy was studied, and the density and specific surface area (SSA) of each snow layer were measured. SSA was measured by CH4 adsorption at 77 K using a volumetric method.
Florent Dominé   +2 more
openaire   +1 more source

Receptive field structure in cortical area 3b of the alert monkey

Behavioural Brain Research, 2002
More than 350 neurons with fingerpad receptive fields (RFs) were studied in cortical area 3b of three alert monkeys. Random dot patterns, which contain all stimulus patterns with equal probability, were scanned across these RFs at three velocities and eight directions to reveal the RFs' spatial and temporal structure.
James J, DiCarlo, Kenneth O, Johnson
openaire   +2 more sources

Emerging Patterns as Structural Alerts for Computational Toxicology

2012
Thanks to significant advances on both the algorithmic and the practical sides, mining graph data has turned into a key domain of data mining. Various domains use graphs to model their data and graph patterns have widely demonstrated their potential, especially in the field of chemoinformatics where chemical structures are commonly modeled as graphs ...
Cuissart, Bertrand   +4 more
openaire   +2 more sources

Genotoxic Impurities: From Structural Alerts to Qualification

Organic Process Research & Development, 2010
The presence of an in cerebro structural alert in a potential or actual impurity, most likely arising as a byproduct or carried-over reagent or starting material, in a drug substance or drug product is merely an indication that the compound may be a DNA-reactive genotoxin.
openaire   +1 more source

Use of Structural Alerts for Reactive Metabolites in the Application SpotRM

Chemical Research in Toxicology
Reactive metabolite (RM) formation is widely accepted as playing a crucial role in causing idiosyncratic adverse drug reactions (IADRs), where the liver is most affected. An important goal of drug design is to avoid selection of drug candidates giving rise to RMs and therefore risk causing problems later on involving IADRs.
openaire   +2 more sources

Paper alert: Structural biology

Current Opinion in Structural Biology, 2001
Máire Convery   +18 more
openaire   +1 more source

Mechanistically driven identification of novel structural alerts for mitochondrial toxicity

Computational Toxicology, 2021
Charles Gong   +2 more
exaly  

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