Results 81 to 90 of about 13,567 (237)

An integrated approach to predict activators of NRF2 - the transcription factor for oxidative stress response

Artificial Intelligence in the Life Sciences
A variety of environmental and physiological conditions can cause oxidative stress that damage cellular components such as DNA, proteins and lipids.
Yaroslav Chushak, Rebecca A. Clewell
doaj   +1 more source

A Pollen‐Enhanced Bionic Mechanoreceptor Induced by Asymmetric Ionic Convection in Hydrogel for Sensory‐Augmented Prostheses

Advanced Science, EarlyView.
This work proposed a pollen‐enhanced bionic mechanoreceptor based on ionic convection. Leveraging the ion anchoring effect of the pollen particle, the output performance could be ∼12 times higher than the original state. By employing deep learning models as AI brains, the feasibility of a sensory‐augmented prosthesis consisting of a pollen‐enhanced ...
Zi Hao Guo, Jingyu Deng, Yanzhang Xu, Chenchen Zhou, Yangshi Shao, Xiong Pu, Munho Kim, Namjoon Cho   +7 more
wiley   +1 more source

ToxBERT: An explainable AI framework for enhancing prediction of adverse drug reactions and structural insights

Journal of Pharmaceutical Analysis
Accurate prediction of drug-induced adverse drug reactions (ADRs) is crucial for drug safety evaluation, as it directly impacts public health and safety.
Yujie He, Xiang Lv, Wulin Long, Shengqiu Zhai, Menglong Li, Zhining Wen   +5 more
doaj   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset. [PDF]

Comput Toxicol, 2021
Pradeep P, Judson R, DeMarini DM, Keshava N, Martin TM, Dean J, Gibbons CF, Simha A, Warren SH, Gwinn MR, Patlewicz G.   +10 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Real-Time Prediction of S-Wave Accelerograms from P-Wave Signals Using LSTM Networks with Integrated Fragility-Based Structural Damage Alerts for Induced Seismicity

Applied Sciences
Early warning of structural damage from induced seismic events requires rapid and reliable ground motion forecasting. This study presents a novel real-time framework that couples a deep learning approach with structural fragility assessment to generate ...
Konstantinos G. Megalooikonomou, Grigorios N. Beligiannis   +1 more
doaj   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Generative Artificial Intelligence and Machine Translators in Spanish Translation of Early Vulnerability Cybersecurity Alerts

Applied Sciences
The increasing reliance on artificial intelligence in cybersecurity has broadened the role of generative artificial intelligence in tasks such as text generation and translation. This study assesses the effectiveness of generative artificial intelligence
Javier Román Martínez, David Triana Robles, Mouhcine El Oualidi Charchmi, Ines Salamanca Estévez, Noemí DeCastro-García   +4 more
doaj   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

Advanced Science, EarlyView.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang, Weisong Liu, Hao Su, Huijuan Cui, Yuanming Wang, Zhiguang Zhu, Chun You, Lingling Zhang   +7 more
wiley   +1 more source